Journal Club 2021-2022 Year to Date Articles
June 29, 2021: Tayon, Farrington
Effect of Long-term Continuous Cardiac Monitoring vs. Usual Care on Detection of Atrial Fibrillation in Patients with Stroke Attributed to Large- or Small-Vessel Disease (KT)
Development and Prospective Validation of a Deep Learning Algorithm for Predicting Need for Mechanical Ventilation (TF)
July 13, 2021: Nyaundi, Hosseini

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TN)

Efficacy and safety of lowering LDL cholesterol in older patients: a systematic review and meta-analysis of randomised controlled trials (PH)

July 27, 2021: Martinez, Tabba

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (LM)

Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial (ST)

August 10, 2021: Anjum, Imphean

Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of Dengue (AA)

Physical Rehabilitation for Older Patients Hospitalized for Heart Failure (DI)

August 24, 2021: Abbas, Hsu

A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease (AA)

Effects of liraglutide on visceral and ectopic fat in adults with overweight and obesity at high cardiovascular risk: a randomised, double-blind, placebo-controlled, clinical trial (SH)

September 7, 2021: Narula, Kasitinon
Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia The REALITY Randomized Clinical Trail (SN)
The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (SK)
September 21, 2021: Kabani, Buddha

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill PatientsA Randomized Clinical Trial, Supplemental 1 and Supplemental 2 (AK)

Cardiovascular and Renal Outcomes with Efpeglenatide in Type 2 Diabetes (MB)
October 5, 2021: Bhattarai, Ou

Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk (UB)

Effect of Salt Substitution on Cardiovascular Events and Death & Protocol (WO)
October 19, 2021: Abbas, Sudheer

Empagliflozin in Heart Failure with a Preserved Ejection Fraction (AA)

Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults with Overweight or Obesity The STEP 4 Randomized Clinical Trial (NS)
November 2, 2021: Nyaundi, Tseng

Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension (TN)

The Effects of Vitamin D and Marine Omega-3 Fatty Acid Supplementation on Chronic Knee Pain in Older US Adults: Results From a Randomized Trial (JT)

November 23, 2021: Farrington, Hsu

Effect of Esophageal Pressure–guided Positive End-Expiratory Pressure on Survival from Acute Respiratory Distress Syndrome A Risk-based and Mechanistic Reanalysis of the EPVent-2 Trial (TF)

Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial (SH)

December 14, 2021: Tumyan, Singh

Vadadustat in Patients with Anemia and Non–Dialysis-Dependent CKD (GT)

Midodrine for the Prevention of Sasovagal Snycope (AS)

January 4, 2022: Bhattarai, Hosseini

Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease (UB)

Effect of a Pulmonary Embolism Diagnostic Strategy on Clinical Outcomes in Patients Hospitalized for COPD Exacerbation A Randomized Clinical Trial (PH)

January 18, 2022: Anjum, Tseng

Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH (AA)

Hospital-treated Infectious Diseases and the Risk of Dementia: a large, multicohort, observational study with a replication cohort (JT)

February 8, 2022: Narula, Brandon

Maintenance or Discontinuation of Antidepressants in Primary Care (SN)

Angiotensin Receptor–Neprilysin Inhibition in Acute Myocardial Infarction (BB)

February 22, 2022: Kabani, Tabba

Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults (AK)

Comparison of Routine Replacement With Clinically Indicated Replacement of Peripheral Intravenous Catheters (ST)

February 28, 2022: Tayon, Imphean

Association of Mental Stress-Induced Myocardial Lischemia With Cardiovascular Events in Patients With Coronary Heart Disease (KT)

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 (DI)

March 22, 2022: Farooq, Ou

CT or Invasive Coronary Angiography in Stable Chest Pain (SF)

Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients with In-Hospital Cardiac Arrest A Randomized Clinical Trial (WO)

April 12, 2022: Tumyan, Kasitinon

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer (GT)

Biologic and Clinical Efficacy of LentiGlobin for Sickle Cell Disease (SK)

April 26, 2022: Bass, Buddha

Prospective, Multicenter, Controlled Trial of Mobile Stroke Units (AB)

Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trial (MB)

May 10, 2022: Kabani, Estes

Calorie Restriction with or without Time-Restricted Eating in Weight Loss and Supplementary Appendix (AK)

Efficacy and Safety of Dapagliflozin According to Frailty in Heart Failure With Reduced Ejection Fraction (WE)

May 24, 2022: Tumyan

High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality (GT)

June 7, 2022: Brandon, Sudheer

Endovascular Therapy for Acute Stroke with a Large Ischemic Region (BB)

Effect of Alirocumab added to high intensity Statin Therapy on Coronary Atherosclerosis in patients with acute myocardial infarction - The PACMAN-AMI Randomized Clinical Trial (NS)
June 14, 2022: Bass, Estes
Influenza Vaccination after Myocardial Infarction (AB)
Risk for Recurrent Venous Thromboembolism and Bleeding With Apixaban Compared With Rivaroxaban: An Analysis of Real-World Data (WE)