| Journal Club 2021-2022 Year to Date Articles |
| June 29, 2021: Tayon, Farrington |
| Effect of Long-term Continuous Cardiac Monitoring vs. Usual Care on Detection of Atrial Fibrillation in Patients with Stroke Attributed to Large- or Small-Vessel Disease (KT) |
| Development and Prospective Validation of a Deep Learning Algorithm for Predicting Need for Mechanical Ventilation (TF) |
| July 13, 2021: Nyaundi, Hosseini |
Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TN) |
Efficacy and safety of lowering LDL cholesterol in older patients: a systematic review and meta-analysis of randomised controlled trials (PH) |
| July 27, 2021: Martinez, Tabba |
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (LM) |
Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial (ST) |
| August 10, 2021: Anjum, Imphean |
Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of Dengue (AA) |
Physical Rehabilitation for Older Patients Hospitalized for Heart Failure (DI) |
| August 24, 2021: Abbas, Hsu |
A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease (AA) |
Effects of liraglutide on visceral and ectopic fat in adults with overweight and obesity at high cardiovascular risk: a randomised, double-blind, placebo-controlled, clinical trial (SH) |
| September 7, 2021: Narula, Kasitinon |
| Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia The REALITY Randomized Clinical Trail (SN) |
| The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (SK) |
| September 21, 2021: Kabani, Buddha |
Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill PatientsA Randomized Clinical Trial, Supplemental 1 and Supplemental 2 (AK) |
| Cardiovascular and Renal Outcomes with Efpeglenatide in Type 2 Diabetes (MB) |
| October 5, 2021: Bhattarai, Ou |
Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk (UB) |
| Effect of Salt Substitution on Cardiovascular Events and Death & Protocol (WO) |
| October 19, 2021: Abbas, Sudheer |
Empagliflozin in Heart Failure with a Preserved Ejection Fraction (AA) |
| Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults with Overweight or Obesity The STEP 4 Randomized Clinical Trial (NS) |
| November 2, 2021: Nyaundi, Tseng |
Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension (TN) |
The Effects of Vitamin D and Marine Omega-3 Fatty Acid Supplementation on Chronic Knee Pain in Older US Adults: Results From a Randomized Trial (JT) |
| November 23, 2021: Farrington, Hsu |
Effect of Esophageal Pressure–guided Positive End-Expiratory Pressure on Survival from Acute Respiratory Distress Syndrome A Risk-based and Mechanistic Reanalysis of the EPVent-2 Trial (TF) |
Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial (SH) |
| December 14, 2021: Tumyan, Singh |
| Vadadustat in Patients with Anemia and Non–Dialysis-Dependent CKD (GT) |
Midodrine for the Prevention of Sasovagal Snycope (AS) |
| January 4, 2022: Bhattarai, Hosseini |
Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease (UB) |
Effect of a Pulmonary Embolism Diagnostic Strategy on Clinical Outcomes in Patients Hospitalized for COPD Exacerbation A Randomized Clinical Trial (PH) |
| January 18, 2022: Anjum, Tseng |
Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH (AA) |
Hospital-treated Infectious Diseases and the Risk of Dementia: a large, multicohort, observational study with a replication cohort (JT) |
| February 8, 2022: Narula, Brandon |
Maintenance or Discontinuation of Antidepressants in Primary Care (SN) |
Angiotensin Receptor–Neprilysin Inhibition in Acute Myocardial Infarction (BB) |
| February 22, 2022: Kabani, Tabba |
Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults (AK) |
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Comparison of Routine Replacement With Clinically Indicated Replacement of Peripheral Intravenous Catheters (ST) |
| February 28, 2022: Tayon, Imphean |
Association of Mental Stress-Induced Myocardial Lischemia With Cardiovascular Events in Patients With Coronary Heart Disease (KT) |
Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 (DI) |
| March 22, 2022: Farooq, Ou |
CT or Invasive Coronary Angiography in Stable Chest Pain (SF) |
Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients with In-Hospital Cardiac Arrest A Randomized Clinical Trial (WO) |
| April 12, 2022: Tumyan, Kasitinon |
Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer (GT) |
Biologic and Clinical Efficacy of LentiGlobin for Sickle Cell Disease (SK) |
| April 26, 2022: Bass, Buddha |
Prospective, Multicenter, Controlled Trial of Mobile Stroke Units (AB) |
Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trial (MB) |
| May 10, 2022: Kabani, Estes |
Calorie Restriction with or without Time-Restricted Eating in Weight Loss and Supplementary Appendix (AK) |
Efficacy and Safety of Dapagliflozin According to Frailty in Heart Failure With Reduced Ejection Fraction (WE) |
| May 24, 2022: Tumyan |
High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality (GT) |
| June 7, 2022: Brandon, Sudheer |
Endovascular Therapy for Acute Stroke with a Large Ischemic Region (BB) |
| Effect of Alirocumab added to high intensity Statin Therapy on Coronary Atherosclerosis in patients with acute myocardial infarction - The PACMAN-AMI Randomized Clinical Trial (NS) |
| June 14, 2022: Bass, Estes |
| Influenza Vaccination after Myocardial Infarction (AB) |
| Risk for Recurrent Venous Thromboembolism and Bleeding With Apixaban Compared With Rivaroxaban: An Analysis of Real-World Data (WE) |