Journal Club 2005-2006 Year to Date Articles
Journal Club current articles and calendar
August 1: Beaujon, Habal, Wang
Effect of Fish Oil on Ventricular Tachyarrythmia and Death in Patients With Implantable Cardioverter Defibrillators. JAMA 2006; 295:2613-2619. (WB)
Comparison of Two Fluid-Management Strategies in Acute Lung Injury. N Engl J Med 2006; 354: 2564-2575. (NH)
Condom Use and the Risk of Genital Human Papillomavirus Infection in Young Women. N Engl J Med 2006; 354: 2645-2654. (SW)
July 18: Govinda, He, Lee

Natalizumab plus Interferon Beta-1a for Relapsing Multiple Sclerosis. N Engl J Med 2006; 354:911-923. (NG)

Dasatinib in Imatinib-Resistant Philadelphia Chromosome-Positive Leukemias. N Engl J Med 2006; 354:2531-2541. (MH)

N-Acetylcysteine and Contrast-Induced Nephropathy in Primary Angioplasty. N Engl J Med 2006; 354:2773-2782. (JL)
May 30: Beeravolu, Palacio, Wilde

Feasibility of Treating Prehypertension with an Angiotensin-Receptor Blocker. S. Julius, and Others. N Engl J Med 2006; 354: 1685-1697. (LB)

Effects of Etanercept in Patients With the Metabolic Syndrome. L. E. Bernstein, and Others. Arch Intern Med. 2006;166:902-908. (NP)

Medication Augmentation after the Failure of SSRIs for Depression. M. H. Trivedi, and Others. N Engl J Med 2006; 354:1243-1252. (DW)
May 16: He, Zhao, Falknor

Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events. D. L. Bhatt, and Others. N Engl J Med 2006; 354: 1706-1717. (MH)

Glycaemia (haemoglobin A1c) and incident ischaemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study. E. Selvin, and Others. Lancet Neurology 2005; 4:821-826. (XZ)

Celecoxib Versus Naproxen and Diclofenac in Osteoarthritis Patients: SUCCESS-I Study. G. Singh, and Others. Am J Med 2006;119: 255-266. (CF)

May 2: Farah, Lan, Raghu

Telephone Care Management To Improve Cancer Screening among Low-Income Women: A Randomized, Controlled Trial. Allen J. Dietrich, and Others. Ann Int Med 2006; 144: 563-571.

Adding Chloroquine to Conventional Treatment for Glioblastoma Multiforme: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Int Med 2006; 144: 337-343. (CL)

Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease. The Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators. N Engl J Med 2006; 354:1567-1577. (AR)

April 18: Galacia, Le, Yandell

A Comparison of Usual Pharmacotherapy for Asthma or Usual Pharmacotherapy Plus Salmeterol. The Salmeterol Multicenter Asthma Research Trial Study Group. Chest. 2006;129:15-26. (DG)

Allergy, histamine 1 receptor blockers, and the risk of multiple sclerosis. A. Alonso, and Others. Neurology 2006; 66:572-575. (ML)

Effect of Rimonabant, a Cannabinoid-1 Receptor Blocker, on Weight and Cardiometabolic Risk Factors in Overweight or Obese Patients: RIO-North America: A Randomized Controlled Trial. RIO-North America: A Randomized Controlled Trial. F. X. Pi-Sunyer, and Others. JAMA 2006; 295: 761-775. (SY)
April 13 : Dacey, Winslow, Yandell
Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma. B. Barlogie and Others. N Engl J Med 2006; 354: 1021 - 1030. (MD)
Calcium plus Vitamin D Supplementation and the Risk of Fractures. R. D. Jackson and Others. N Engl J Med 2006; 354: 669-83. (HW)
Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis. D. O. Clegg, and Others. N Engl J Med 2006; 354: 795-808. (SY)
April 4 : Das, Dunagin, Mera

Eplerenone Reduces Mortality 30 Days After Randomization Following Acute Myocardial Infarction in Patients With Left Ventricular Systolic Dysfunction and Heart Failure. B. Pitt, and Others. J Am Coll Cardiol 2005 46: 425-431. (SD)

Incidence of Venous Thromboembolism and Its Effect on Survival Among Patients With Common Cancers. Arch Intern Med. 2006;166:458-464. (RD)

Emergence of Community-Acquired Methicillin-Resistant Staphylococcus aureus USA 300 Clone as the Predominant Cause of Skin and Soft-Tissue Infections. M. D. King, and Others. Annals Int Med 2006; 144:309-317. (JM)
March 31: Hastie, Lone, Lee

Efficacy of transesophageal echocardiography–guided cardioversion of patients with atrial fibrillation at 6 months: A randomized controlled trial. A. L. Klein AL, and Others. Am Heart J 2006; 151: 380-389. (JH)

Coffee, CYP1A2 Genotype, and Risk of Myocardial Infarction. M. C. Cornelis; and Others. JAMA. 2006;295:1135-1141. (JL)

Evidence of a Role of Tumor Necrosis Factor alpha in Refractory Asthma. N Engl J Med 2006: 354:697-708. (JYL)

March 21: Abdulla, Bassi, Beeravolu

Febuxostat compared to allopurinol in Patients with hyperuricemia and Gout. M. A. Becker, and Others. N Engl J Med 2005; 353: 2450-2461. (ZA)

Comparing yoga, exercise, and a self-care book for chronic low back pain: a randomized, controlled trial. K. J. Sherman, and Others. Ann Intern Med 2005; 143: 849-56. (SB)

NXY-059 for Acute Ischemic Stroke. K. R. Lees, and Others. N Engl J Med 2006: 354:588-600. (LB)
March 1: Farah, Lan, Moran

Influence of Sleep Stages on Esophago-Upper Esophageal Sphincter Contractile Reflex and Secondary Esophageal Peristalsis.J. S. Bajaj, and Others. Gastroenterology 2006; 130: 17-25. (NF)

A Comparison of Letrozole and Tamoxifen in Postmenopausal Women with Early Breast Cancer. The Breast International Group (BIG) 1-98 Collaborative Group. N Engl J Med 2005; 353:2747-2757. (CL)

A Placebo-Controlled Trial of Itopride in Functional Dyspepsia. G. Holtmann and Others. N Engl J Med 2006; 354:832-840. (KM)

February 21: Dunagin, Le

Watchful Waiting vs Repair of Inguinal Hernia in Minimally Symptomatic Men. A Randomized Clinical Trial. RJ Fitzgibbons, and Others. JAMA. 2006;295:285-292. (RD)

MELD score is a better prognostic model than Child-Turcotte-Pugh score or Discriminant Function score in patients with alcoholic hepatitis. W Srikureja, and Others. J Hepatology 2005; 42: 700-706. (ML)

February 7 : Govinda, Palacio, Wilde

Efficacy of Human Papillomavirus-16 Vaccine to Prevent Cervical Intraepithelial Neoplasia: A Randomized Controlled Trial. Obstet Gynecol 2006 107: 18-27. (NG)

Efficiency of curative and prophylactic treatment with rituximab in ADAMTS13-deficient thrombotic thrombocytopenic purpura: a study of 11 cases. Blood 2005; 106:1932-1937. (NP)

Efficacy and Safetey of Benazapril for Advanced Chronic Renal Insufficiency. N Engl J Med 2006; 354: 131-140 (DW)

January 24: Lee, Galicia, Raghu

Risk of Death in Elderly Users of Conventional vs. Atypical Antipsychotic Medications . N Engl J Med 2005; 353:2335-2341. (JYL)

Tumour necrosis factor (TNF) as a novel therapeutic target in symptomatic corticosteroid dependent asthma. P H Howarth, and Others. Thorax 2005; 60: 1012-1018 (DG)

Risk of Hepatocellular Carcinoma Across a Biological Gradient of Serum Hepatitis B Virus DNA Level. JAMA. 2006;295:65-73. (AR)

January 10 : Lone, Lee, Zhao, Hastie

Aspirin Administered at Bedtime, But Not on Awakening, Has an Effect on Ambulatory Blood Pressure in Hypertensive Patients. J Am Coll Cardiol, 2005; 46:975-983. (JL)

Risk of Death in Elderly Users of Conventional vs. Atypical Antipsychotic Medications . N Engl J Med 2005; 353:2335-2341. (JYL)

Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005; 353:2462-2476. (XZ)

Validation of a Behavioral Pain Scale in Critically Ill, Sedated, and Mechanically Ventilated Patients. Anesth Analg 2005;101:1470-1476. (JH)
December 20: Mera, Abdulla, McDonald

Beta-Blockers to Prevent Gastroesophageal Varices in Patients with Cirrhosis. Groszmann R. J., and Others for the Portal Hypertension Collaborative Group. N Engl J Med 2005; 353:2254-2261. (JM)

Sildenafil Citrate Therapy for Pulmonary Arterial Hypertension. N Galiè, and Others for the Sildenafil Use in Pulmonary Arterial Hypertension (SUPER) Study Group. N Engl J Med 2005; 353:2148-2157. (ZA)

Habitual Caffeine Intake and the Risk of Hypertension in Women. WC Winkelmayer, and Others. JAMA. 2005;294:2330-2335. (HM)
December 6 : Moran, Das, Falknor

Mycophenolate Mofetil or Intravenous Cyclophosphamide for Lupus Nephritis. E. M. Ginzler and Others. N Engl J Med 2005; 353:2219-2228. (KM)

Randomized Trial of Lifestyle Modification and Pharmacotherapy for Obesity. T. A. Wadden and Others. N Engl J Med 2005; 353:2111-2120. (SD)

High-Dose Acetylcysteine in Idiopathic Pulmonary Fibrosis. M. Demedts and Others. N Engl J Med 2005; 353: 2229-2242. (CF)

November 22 : Dacey, He, Winslow

Effect of a High-Carbohydrate Versus a High—cis-Monounsaturated Fat Diet on Blood Pressure in Patients With Type 2 Diabetes. Diabetes Care. 2005;28:2607-2612. (MD)

Continuous Positive Airway Pressure for Central Sleep Apnea and Heart Failure. N Engl J Med 2005; 353:2025-2033. (MH)

Prognostic Significance of Dyspnea in Patients Referred for Cardiac Stress Testing. N Engl J Med 2005; 353:1889-1898. (HW)

November 8 : Bassi, Dunagin, Lone
Inhaled Insulin Improves Glycemic Control When Substituted for or Added to Oral Combination Therapy in Type 2 Diabetes: A Randomized, Controlled Trial. Rosenstock, and Others. Annals Int Med 2005;143: 549-558. (SB)

Relevance of Urine Telomerase in the Diagnosis of Bladder Cancer. M A Sanchini, andn Others. JAMA 2005; 294: 2052-2056. (RD)

Early Invasive versus Selectively Invasive Management for Acute Coronary Syndromes. The Invasive versus Conservative Treatment in Unstable Coronary Syndromes (ICTUS) Investigators. N Engl J Med 2005; 353:1095-1104. (JL)

October 25: Govinda, Le, McDonald

Abatacept for Rheumatoid Arthritis Refractory to Tumor Necrosis Factor Inhibition. M. C. Genovese, and Others. N Engl J Med 353:1114-1123. (NG)

Meta-Analysis: Computed Tomographic Colonography. B. P. Mulhall, and Others. Annals Int Med 2005; 142: 635-650. (ML)
Effect of Smoking Reduction on Lung Cancer Risk. N. S. Godtfredsen and Others. JAMA. 2005;294:1505-1510. (HM)
October 4: Falknor, Farah, Hastie, Lee
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Andrew J Molyneux , et al. The Lancet 2005; 366:809-817. (CF)
Modafinil for Excessive Sleepiness Associated with Shift-Work Sleep Disorder. C.A. Czeisler, and Others for the U.S. Modafinil in Shift Work Sleep Disorder Study Group.  New Engl J Med 2005;353:476-486. (NF)
Effect of Statin Use Within the First 24 Hours of Admission for Acute Myocardial Infarction on Early Morbidity and Mortality. G. C Fonarow, and Others. Am J Cardiol. 2005; 96: 611-616. (JH)

Clinical and Radiographic Correlates of Primary and Reactivation Tuberculosis: A Molecular Epidemiology Study. E. Geng, and Others. JAMA. 2005;293:2740-2745. (JYL)
September 20:  He, Mera, Palacio
Cobalamin-responsive disorders in the ambulatory care setting: unreliability of cobalamin, methylmalonic acid, and homocysteine testin. L. R. Solomon Blood 2005 105: 978-985. (MH)
Antibacterial Prophylaxis after Chemotherapy for Solid Tumors and Lymphomas. M. Cullen and Others . N Engl J Med 2005; 353: 988-98. (JM)
The Starting Dose of Levothyroxine in Primary Hypothyroidism Treatment: A Prospective, Randomized, Double-blind Trial Annemieke Roos; Suzanne P. Linn-Rasker; Ron T. van Domburg; Jan P. Tijssen; Arie Berghout. Arch Intern Med. 2005;165:1714-1720. (NP)
September 6:  Lan, Beeravolu, Dacey, Winslow
Benign Breast Disease and the Risk of Breast Cancer. N Engl J Med 2005;353:229-237. (CL)
Daily and Cyclic Parathyroid Hormone in Women Receiving Alendronate. F. Cosman and Others. N Engl J Med 2005; 353:566-75.
A Randomized, Double-Blind, Placebo-Controlled Trial of Pramipexole, a Dopamine Agonist, in Patients With Fibromyaglia Receiving Concomitant Medications. Arthritis & Rheumatism 2005; 52:2495-2505.(MD)
Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis. N Engl J Med 2005; 353:369-74. (HW)
August 29: Raghu, Das, Zhao
Improved Glycemic Control With No Weight Increase in Patients With Type 2 Diabetes After Once-Daily Treatment With the Long-Acting Glucagon-Like Peptide 1 Analog Liraglutide (NN2211. A 12-week, double-blind, randomized, controlled trial. Diabetes Care 2004; 27:1335-1342. (AR)
Perioperative Beta-Blocker Therapy and Mortality after Major Noncardiac Surgery. N Engl J Med 2005; 353:349-361. (SD)
Eight-Year Follow-Up of Patients With Permanent Vena Cava Filters in the Prevention of Pulmonary Embolism: The PREPIC (Prévention du Risque d’Embolie Pulmonaire par Interruption Cave) Randomized Stud. The PREPIC Study Group. Circulation 2005 112: 416 - 422. (XZ)
August 2: Moran, Heer, Abdulla
Meta-Analysis: The Effect of Steroids on Survival and Shock during Sepsis Depends on the Dose. Ann Int Med 2004; 141:47-57. (KM)
Dipyridamole for Preventing Recurrent Ischemic Stroke and Other Vascular Events: A Meta-Analysis of Individual Patient Data From Randomized Controlled Trials. Stroke 2005 36: 162 - 168. (GH)
Amiodarone versus Sotalol for Atrial Fibrillation. N Engl J Med 2005; 352:1861-1872. (ZA)
July 19: Galicia, Yandell, Wilde 
Bed Rest or Ambulation in the Initial Treatment of Patients With Acute Deep Vein Thrombosis or Pulmonary Embolism*. Findings From the RIETE Registry. Chest. 2005;127:1631-1636. (DG)
Operating Characteristics of Prostate-Specific Antigen in Men With an Initial PSA Level of 3.0 ng/mL or Lower. JAMA. 2005;294:66-70. (SY)
Surgical stabilisation of the spine compared with a programme of intensive rehabilitation for the management of patients with chronic low back pain: cost utility analysis based on a randomised controlled trial. BMJ, doi:10.1136/bmj.38441.429618.8F (published 23 May 2005) (DW)
JUNE 16:  Farah, Zamanian, Fernandes
Use of Ambulatory Overnight Oximetry to Investigate Sleep Apnea in a General Internal Medicine Practice. Mayo Clin Proc. 2005;80:455-462. (NFarah)
Statins and the Risk of Colorectal Cancer. N Engl J Med 2005; 352:2238-2239. (MZ)
Radical Prostatectomy versus Watchful Waiting in Early Prostate Cancer, Bill-Axelson, Holmberg, Ruutu, and Others. N Eng J Med May 12, 2005; 352:1977-1984. (NFernandes)