Recent reports in Science and Medicine for April 2004

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April 30

Weekend Reading - Basic Science and general interest articles

  1. § Activator of G Protein Signaling 3: A Gatekeeper of Cocaine Sensitization and Drug Seeking. Bowers, et al. Neuron 2004; 42, 269-281.[Science Now report]
  2. § S-Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function. Chung, et al. Science 2004 Science 10.1126/science. 1093891[Eurekalert: Nitric oxide links bulk of sporadic and familial Parkinson's disease]
  3. § Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects Science 2004; 30: 600-602. [Eurekalert report: Scientists correct cystic fibrosis defect in mice with turmeric extract. New Scientist report]
  4. April 30, 2004 is the last day New and Generic Drug Approvals 1998-2004, will be updated. Starting May 1, 2004, please use Drugs@FDA for all drug approval information.
  5. FDA: Orange Book Information Data Files
  6. The Tribulations of Clinical Trials. Efforts are afoot to improve the output of the drug research pipeline [The Scientist report]
  7. CD8aa -mediated survival and differentiation of CD8 memory T cell precursors, L.T. Madakamutil et al., Science, 304:590-593, April 23, 2004.[The Scientitst: Expression of a specific CD8 molecule enables the development of a memory T-cell pool]
  8. What Residents Don't Know about Physician-Pharmaceutical Industry Interactions. Watkins and Kimberly, Acad Med 2004 79: 432-437. [Eurekalert: Medical residents need training to interact with pharmaceutical representatives]
  9. Does the type of flooring affect the risk of hip fracture? Age Ageing 2004 33: 242-246.
  10. § Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype. PNAS published April 26, 2004, 10.1073/pnas.0402133101
  11. § Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats. PNAS published April 26, 2004, 10.1073 {Eurekalert review]
  12. § Metabolic syndrome without obesity: Hepatic overexpression of 11-hydroxysteroid dehydrogenase type 1 in transgenic mice. PNAS published April 26, 2004, 10.1073
  13. Health Affairs (March/April) BEYOND MANAGED CARE
  14. The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nature: Genetics 25 April 2004 | doi:10.1038/ng1352

April 29

  1. In This Issue of Archives of Internal Medicine 2004;164:823.
  2. Latency and Persistence of Respiratory Syncytial Virus Despite T Cell Immunity. Am. J. Respir. Crit. Care Med. 2004; 169: 801-805.[Eurekalert: Cold virus can 'hit and hide']
  3. § Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr 2004 79: 537-543.
  4. Left Ventricular Hypertrophy Accompanies Obesity in Young, Healthy Women [Medscape report from J Am Coll Cardiol 2004;43:1399-1404.]
  5. § Cochrane Corner: Antiplatelet Therapy for Preventing Stroke and Other Vascular Events After Carotid Endarterectomy Engelter and Lyrer Stroke 2004 35: 1227 - 1228
  6. § Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. LS Gross, L Li, ES Ford, and S Liu. Am J Clin Nutr ; 79: 774
  7. Smoking linked to more than 60 percent of overall cancer death burden in black men [Eurekalert report from the May issue of the journal Preventive Medicine -full text is available]
  8. Science reporting to the public: Does the message get twisted? CMAJ 2004 170: 1415-1416.
  9. § Efficacy of pergolide in treatment of restless legs syndrome: The PEARLS Study. Neurology 2004 62: 1391-1397.
  10. § Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy: Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2004 62: 1252-1260.

April 28

  1. Lancet Volume 363, Number 9418   24 April 2004
  2. BMJ 24 April 2004 (Vol 328, No 7446)
  3. Community-Onset Methicillin-Resistant Staphylococcus aureus Associated with Antibiotic Use and the Cytotoxin Panton-Valentine Leukocidin during a Furunculosis Outbreak in Rural Alaska. Baggett, et al. JID 2004; 189; 1565. [Eurekalert report on risk factors for bacterial resistance]

April 27

  1. New England Journal of Medicine Volume 350 April 22, 2004 Number 17  Article Summaries
  2. § Effectiveness of Implementing the Agency for Healthcare Research and Quality Smoking Cessation Clinical Practice Guideline: A Randomized, Controlled Trial. JNCI 2004; 96: 594-603. [Medscape report]
  3. § Tobacco Control in the Physician’s Office: A Matter of Adequate Training and Resources. JNCI 2004; 96: 573-575.
  4. Relationship between Body Weight Gain and Significant Knee, Hip, and Back Pain in Older Americans. Obes Res 2003 11: 1159-1162.
  5. Consensus Development Conference on Antipsychotic Drugs and Obesity and Diabetes. American Diabetes Association, American Psychiatric Association, American Association of Clinical Endocrinologists, and North American Association for the Study of Obesity. Diabetes Care 27:596-601, 2004 and Obes Res 2004 12: 362-368.

April 26

  1. This Week in JAMA. 2004;291:1803.
  2. Water Potentiates the Pressor Effect of Ephedra Alkaloids. Circulation 2004 109: 1823 - 1825.
  3. A Controlled, Randomized, Delayed-Start Study of Rasagiline in Early Parkinson Disease. Parkinson Study Group. Arch Neurol. 2004;61:561-566.[Starting Rasagiline Early May Reduce Functional Decline in Parkinson's Disease Medscape review]
  4. Oncology Physician and Nurse Practices and Attitudes Regarding Offering Clinical Trial Results To Study Participants. J Natl Cancer Inst 2004; 96: 629-632.
  5. § Effectiveness of Implementing the Agency for Healthcare Research and Quality Smoking Cessation Clinical Practice Guideline: A Randomized, Controlled Trial. J Natl Cancer Inst 2004; 96: 594-603.

April 23

Weekend Reading - Basic Science and general interest articles

  1. § Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Fontana, et al. PNAS published April 19, 2004, 10.1073/pnas.0308291101.[Science NOW and Medscape reviews]
  2. § A Mouse With Two Mothers [New Scientist and Science NOW report from Nature]
  3. New Support for 'Hygiene Hypothesis' [Science now report]
  4. 'Use It Or Lose It' Warning Rings True When It Comes To Exercise [Science Daily report from Health Psychology]
  5. ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease. Lustbader, et al. Science 2004; 304: 448-452.
  6. Imaging Study Reveals Brain Function Of Poor Readers Can Improve [Science Daily report from Biological Psychiatry ]
  7. New Markers for ALS [Science NOW report from the Federation of Societies for Experimental Biology meeting ]
  8. More than a million Americans abuse presription drugs. {News release from the American Journal of Public Health.]
  9. FDA: A Message About HIPAA Compliance for Reporters to FDA MedWatch.
  10. FDA Approves Apokyn for the Acute Treatment of Episodes of Immobility in Parkinson’s Patients
  11. Medscape CME: Management of Atherothrombosis With Clopidogrel in High-Risk Patients With Recent Transient Ischemic Attacks or Ischemic Stroke (MATCH): Trial Design and Rationale
  12. More Than A Million Americans Abuse Prescription Drugs[Science Daily report from the American Journal of Public Health.]
  13. Researchers Identify Virus Gene Involved In Tumor Cell Growth, Spread [Science Daily report from Cancer Research.]
  14. Newborn Testing for Immune Disorders Could Save Lives. [Duke University report from Annual Review of Immunology]
  15. Fat cell hormone causes weight loss [Eurekalert report from the May issue of Nature Medicine.]

April 22

  1. Annals of Internal Medicine 20 April 2004 Volume 140 Issue 8
  2. Helicobacter pylori eradication releases prolonged increased acid secretion following omeprazole treatment. Gillen, et al . Gastroenterology 2004 doi:10.1053.
  3. Homocysteine and Folic Acid Are Inversely Related in Black Women With Preeclampsia. Hypertension published April 19, 2004, 10.1161 [Medscape report]
  4. § The Burden of Chronic Disease: The Future is Prevention. George E. Hardy preventing Chronic Disease Volume 1: No. 2, April 2004 (CDC)

April 21

  1. This week in the BMJ 17 April 2004 (Vol 328, No 7445)
  2. The Lancet Volume 363, Number 9417     17 April 2004
  3. B cell-dependent TCR diversification. João, et al. J. Immunology 2004; 172: 4709 – 4716.[Eurekalert report: Researchers restore lost immunity -- Possible breakthrough for AIDS]

April 20

  1. New England Journal of Medicine Volume 350 - April 15, 2004 Number 16
  2. FDA Approves Protonix IV, Vitality 2, and Generic Ribavirin; Canada Approves Enbrel, EC Approves Xenical [Medscape reveiw]
  3. Seal of approval scheme needed for complementary and alternative websites [Eurekalert report from Annals of Oncology]

April 19

  1. This Week in JAMA 2004;291:1673.
  2. § Practice Parameter: Recurrent stroke with patent foramen ovale and atrial septal aneurysm: Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2004 62: 1042-1050.
  3. Emotional Reaction of Varsity Athletes to Sport-Related Concussion JSEP, 26(1), March 2004 [Science Daily review: Concussion Causes Emotional Disturbances]
  4. Lung Cancer Now Leading Cause Of Cancer Death In Women [Science Daily report]
  5. Specifying alcohol-related brain-damage among heavy social drinkers [Eurekalert report from April issue : Alcoholism: Clinical & Experimental Research]
  6. Preventing Provider Errors: Online Total Parenteral Nutrition Calculator. Pediatrics 2004; 113: 748-753.
  7. Recall and detection rates in screening mammography: A review of clinical experience: Implications for practice guidelines. Gur, et al. Cancer 2004;100: 1590-1594. Editorial: The never-ending controversies of screening mammography: What is the appropriate callback rate for women undergoing screening mammographic examination?
  8. Computer System Spots Breast Lesion Misclassification [Medscape review from Radiology 2004;230:820-823.]
  9. § Health Literacy Low in America: Report [Medscape report from the Institute of Medicine (IOM). New Scientist report]
  10. Gabapentin Effective in Neuropathic Pain of Spinal Cord Injury [Medscape review from the April 1 issue of Spine.]

April 16

Weekend Reading - Basic Science and general interest articles

  1. The Genetics of Wheezing [Science now report on report in Science 9 April 2004: Characterization of a Common Susceptibility Locus for Asthma-Related Traits. Laitinen, et al (subscribers)]
  2. Australian 'mud football' game sickens players [Eurekalert report Clinical Infectious Diseases]
  3. Premalignant lesions in the contralateral ovary of women with unilateral ovarian carcinoma, Gyn Oncology 2004; 93: 69-77.(Science Direct access) Eurekalert report
  4. Study shows lower than expected allergic-like events following second prescription of penicillin. J Allergy & Clin Imm. [Science Direct access.]
  5. Fibromyalgia Pain: Do We Know the Source? Roland Staud. [Medscape review of Curr Opin Rheumatol 16(2):157-163, 2004.]
  6. § Researchers Isolate Gene For Crohn's Disease [Science Daily report of April 11 Nature Genetics .]
  7. Drug Company Kickbacks: Pharmaceutical Companies Offer Doctors Free Trips, Gifts for Prescriptions [ABC News: Drug Company Accused of Bribing Doctors]
  8. Popular citrus soda culprit in patient’s medical mystery [Vanderbilt MC news, Science Daily]
  9. Prescription Of Opioids For Back Pain Needs Improvement [Duke MC news report from Spine April 15, 2004 (no open access)]
  10. Newborn lambs' central heating system could aid fat busting in humans [Eurekalert and Science Daily reports]
  11. § Council on Family Health Offers Medicine Use Information for Seniors: Medicines and You: A Guide for Older Adults [from FDA]
  12. Young female chimps outlearn their brothers [New Scientist report from Nature]
  13. Highlights of the American Academy of Pain Medicine [Medscape review]
  14. Alcohol Intake and Risk of Dementia [Medscape report from Journal of the American Geriatrics Society]
  15. The Spring 2004 Allergy Capitals by the Asthma and Allergy Foundation of America

April 15

  1. Abilify (aripiprazole): FDA and Bristol-Myers Squibb WARNINGS section of labeling amended to describe the risk of hyperglycemia and diabetes in patients taking Abilify. FDA asked all manufacturers of atypical antipsychotic medications to add this Warning statement to labeling.
  2. In This Issue of Archives of Internal Medicine 2004;164:696.
  3. Review: Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy . CMAJ 2004 170: 1263-1273
  4. Effects of Diet and Exercise on Obesity-Related Vascular Dysfunction in Children. Circulation 2004: published online
  5. § High-Density Lipoproteins Neutralize C-Reactive Protein Proinflammatory Activity. Circulation 2004: published online
  6. § Effects of Acute Mental Stress and Exercise on T-Wave Alternans in Patients With Implantable Cardioverter Defibrillators and Controls. Circulation 2004: published online
  7. Atrial Natriuretic Peptide Gene Polymorphisms and Risk of Ischemic Stroke in Humans. Stroke. 2004;35:814.
  8. Early Cognitive Decline After CABG Points to Subsequent Decline [Medscape report from the April issue of Heart.]
  9. Office Spirometry Significantly Improves Early Detection of COPD in General Practice: The DIDASCO Study Chest 2004 125: 1394-1399.
  10. Environmental Tobacco Smoke May Induce Early Lung Damage in Healthy Male Adolescents.Chest 2004 125: 1387-1393.
  11. Symptoms, Respirator Use, and Pulmonary Function Changes Among New York City Firefighters Responding to the World Trade Center Disaster*. Chest. 2004;125:1256-1264.
  12. Respiratory Symptoms and Physiologic Assessment of Ironworkers at the World Trade Center Disaster Site* . Chest. 2004;125:1248-1255.
  13. § Medium-Term Survival after Hospitalization with Community-Acquired Pneumonia. Am. J. Respir. Crit. Care Med. 2004; 169: 910-914.
  14. Statin and aspirin therapy are associated with decreased rates of choroidal neovascularization among patients with age-related macular degeneration. Am J Ophthal. 2004; 137: 615-624. [Eurekalert review]
  15. The Prevalence of Diabetic Retinopathy Among Adults in the United States. The Eye Diseases Prevalence Research Group* Arch Ophthalmol. 2004;122:552-563.
  16. § Causes and Prevalence of Visual Impairment Among Adults in the United States. The Eye Diseases Prevalence Research Group* Arch Ophthalmol. 2004;122:477-485.

April 14

  1. § The ß1 subunit of the Ca2+-sensitive K+ channel protects against hypertension. J. Clin. Invest. 2004 113: 955-957.
  2. Functional obstruction: the renal pelvis rules. J Clin. Invest. 2004 113: 957-959.
  3. Bim, Bad, and Bax: a deadly combination in epileptic seizures. J. Clin. Invest. 2004 113: 960-962.
  4. § Aspirin Use and Pancreatic Cancer Mortality in a Large United States Cohort. J Natl Cancer Inst 2004; 96: 524-528.[Medscape report ]
  5. § A Prospective Study of Plasma C-Peptide and Colorectal Cancer Risk in Men. J Natl Cancer Inst 2004; 96: 546-553. [Medscape report]
  6. § Breast Cancer Risk After Caloric Restriction During the 1944–1945 Dutch Famine.J Natl Cancer Inst 2004; 96: 539-546.
  7. EDITORIAL: Déjà Vu for Breast Cancer Two? J Natl Cancer Inst 2004; 96, 497-499
  8. Sildenafil Effectively Treats PPH: First Randomized Controlled Trial Results [Medscape report from J Am Coll Cardiol 2004;43:1149-1153.(CardioSource)]
  9. § FDA and Novartis revise WARNINGs on Clozaril (clozapine tablets) describing the increased risk of hyperglycemia and diabetes.
  10. § IOM Recommends Action on Supplements [ Dietary Supplements: A Framework for Evaluating Safety (2004)]
  11. End of life ICU use may require re-evaluation. Eurekalert report from Critical Care Medicine (no online acess)
  12. MMWR April 9, 2004 / Vol. 53 / No. 13

April 13

  1. Lancet Volume 363, Number 9416   10 April 2004
  2. British Medical Journal 10 April 2004 (Vol 328, No 7444)
  3. § Special Reports: The Critical Care Professional Societies Address the Critical Care Crisis in the United States. Chest 2004 125: 1512-1513.
  4. The Critical Care Crisis in the United States: A Report From the Professio. Chest 2004 125: 1514-1517.
  5. The Critical Care Medicine Crisis: A Call for Federal Action: A White Paper From the Critical Care Professional Societies. Chest 2004 125: 1518-1521. [Eurekalert report]
  6. High Prevalence of Acquired Antimicrobial Resistance Unrelated to Heavy Antimicrobial Consumption J Infect Dis 2004;189:1291-1294.
  7. Daptomycin: Another Novel Agent for Treating Infections Due to Drug-Resistant Gram-Positive Pathogens Clin Inf Dis 2004;38:994-1000
  8. § High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome–positive chronic phase chronic myeloid leukemia. Blood 2004 103: 2873-2878.
  9. § Exaggerated Exercise Blood Pressure is Related to Impaired Endothelial Vasodilator Function. Am J Hypertension; 2004;17: 314-320.- Science Direct [Eurekalert report]
  10. FDA Announces Rule Prohibiting Sale of Dietary Supplements Containing Ephedrine Alkaloids Effective April 12

April 12

  1. New England Journal of Medicine - Volume 350 April 8, 2004 Number 15  Article Summaries

April 9

Weekend Reading - Basic Science and general interest articles

  1. § The Fat-Brain Axis Enters a New Dimension. Science, Vol 304, Issue 5667, 63-64 , 2 April 2004
  2. What Do the Results of SCD-HeFT, PAVE, and DINAMIT Mean for Clinical Practice? [Medscape review article]
  3. § Embryonic Stem Cells Induced To Develop Into Bone Marrow And Blood Cells. Richard K. Burt, M.D., and colleagues in April issue of The Journal of Experimental Medicine [Science Daily]
  4. § Activity Of Calcium-handling Gene Appears To Prevent Cardiac Arrhythmias [Science Daily report from the early online edition of Proceedings of the National Academy of Sciences]
  5. Peroxisome Proliferator-Activated Receptor Agonists Increase Nitric Oxide Synthase Expression in Vascular Endothelial Cells. Arterioscler Thromb Vasc Biol 2004 24: 658 - 663. See also the Editorial: Regulation of Endothelial Nitric Oxide Synthase by PPAR Agonists: Molecular and Clinical Perspectives. Arterioscler Thromb Vasc Biol 2004 24: 619 - 621
  6. FDA Public Health Notification: Paralysis from Absorbable Hemostatic Agent
  7. Medscape report: FDA Approves Zyprexa IM, New Indications for Cipro and Vioxx, OraQuick HIV-1 Test, Contour SE, CapSureFix Pacing Lead, and D-Stat Dry 3x3 Hemostatic Bandage
  8. A Walnut Diet Improves Endothelial Function in Hypercholesterolemic Subjects. A Randomized Crossover Trial. Circulation 2004: published online. [Medscape report: U.S. Regulators OK Walnut Health Claims]
  9. A Distinct Role for Norepinephrine in Memory Retrieval. Murchison, et al. Cell April 2, 2004: 117. [Science Daily report]
  10. Chocolate in pregnancy keeps baby happy. [New Scientist report form Early Human Development (vol 76, p 139)]

April 8

  1. Thyroid cancer study simplifies follow-up exams for patients [Eurekalert report from The Journal of Nuclear Medicine]
  2. § 'Telling people what they want to believe' Dean Ornish looks at Atkins and other low-carb diets in Journal of the American Dietetic Association [Eurekalert]
  3. § Management and outcomes of transient ischemic attacks in Ontario. CMAJ 2004 170: 1099-1104;
  4. Early risk of stroke after a transient ischemic attack in patients with internal carotid artery disease. CMAJ 2004 170: 1105-1109.
  5. Commentary: Early risk of stroke after transient ischemic attack: back to the future. CMAJ 2004 170: 1113-1114
  6. This Week in JAMA. 2004;291:1535.

April 7

  1. Mayo Clinic Proceedings April 2004  Volume 79  Number 4
  2. Upregulation of Angiotensin-Converting Enzyme 2 After Myocardial Infarction by Blockade of Angiotensin II Receptors. Hypertension published March 8, 2004, 10.116
  3. § Blood pressure may predict recurrent cardiovascular events in women. Circulation 2004 on-line rapid access.
  4. § Hyperventilation-Induced Hypotension During Cardiopulmonary Resuscitation. Circulation 2004: published online before print .
  5. § Clinical Pharmacology of Platelet, Monocyte, and Vascular Cyclooxygenase Inhibition by Naproxen and Low-Dose Aspirin in Healthy Subjects. Capone, et al..Circulation 2004 109: 1468 - 1471
  6. § Effects of Diet and Exercise on Obesity-Related Vascular Dysfunction in Children. Circulation 2004: published online [Medscape and Eurekalert reviews]
  7. Intensive diabetes management yields positive results, according to Pittsburgh project [Eurekalert the April issue of Clinical Diabetes]
  8. Pooled Analysis of Fluorouracil-Based Adjuvant Therapy for Stage II and III Colon Cancer: Who Benefits and by How Much? JCO published online [Eurekalert].
  9. Blood Pressure Response to Caffeine Shows Incomplete Tolerance After Short-Term Regular Consumptio. Hypertension 2004 43: 760-765.
  10. Acetaminophen Use Prospectively Linked With Asthma in Women Am J Respir Crit Care Med 2004;169:836-841.
  11. Annals of Internal Medicine 6 April 2004 Volume 140 Issue 7

April 6

  1. British Medical Journal 3 April 2004 (Vol 328, No 7443)
  2. MMWR Recommended Childhood and Adolescent Immunization Schedule --- United States, January--June 2004
  3. Lancet Volume 363, Number 9415     03 April 2004
  4. Medical genetics: A marker for Stevens–Johnson syndrome 48. Nature 2004 doi:10.1038/428486a [Duke Univ. news release]
  5. Meta-analysis of Cephalosporin Versus Penicillin Treatment of Group A Streptococcal Tonsillopharyngitis in Children. Pediatrics 2004; 113: 866-882.
  6. Flavor Programming During Infancy. Pediatrics 2004; 113: 840-845.
  7. Low vitamin B12 is associated with poorer memory in older people with high risk for Alzheimer's. Full-text pdf file from Neuropsychology and Eurekalert news report.

April 5

  1. New England Journal of Medicine Volume 350 . April 1, 2004 . Number 14 Contents
  2. Blood Pressure Response to Caffeine Shows Incomplete Tolerance After Short-Term Regular Consumption. Lovallo, et al. Hypertension 2004 43: 760-765. [Editorial: Effect of Caffeine on Blood Pressure Beyond the Laboratory. Hypertension 2004 43: 724-725]

April 2

Weekend Reading - Basic Science and general interest articles

  1. Scientists compare rat genome with human, mouse [Eurekalert report from the journal Nature]
  2. Kim and Yin. Antimicrob. Agents Chemother. 2004. 48: 1017-1020. [Eurekalert review]
  3. The Accidental Addict: Clearing away the myths surrounding the OxyContin "epidemic." Szalavitz Slate Magazine March 25, 2004.
  4. Dream Rebound: The Return of Suppressed Thoughts in Dreams. Wegner, Psychological Science 2004;15: 232-236(5)
  5. Early Vitamin E Supplements Stem Development Of Hallmark Alzheimer's Symptoms In Mice [Science Daily report from The FASEB Journal.]
  6. Researchers discover gene mutations that 'ignore' stress, lead to heart failure [Eurekalertreport from Nature Genetics]
  7. Aortoiliac Insufficiency: Long-term Experience with Stent Placement for Treatment. Radiology published online [Eurekalert]
  8. FDA News: FDA Approves First Oral Fluid Based Rapid HIV Test Kit
  9. FDA News: FDA Enhances Safeguards For Consumers Who May Have Special Sensitivities to Certain Commonly Used Over-the-Counter Drug Ingredients
  10. Older Adults' Chronic Pain May Dull Appetite [News report from the Journal of the American Geriatric Society - not online]
  11. Reports from the 95th annual meeting of the American Association for Cancer Research
  12. Having emergency contraception at home does not boost rate of unprotected sex among teens [Eurekalert report from the J Ped and Adol Gyne]
  13. New therapeutic approach for sickle cell disease[Eurekalert report from the April issue of Nature Medicine.]
  14. § Top 10 actual causes of death in the United States CDC Report
  15. Autism gene found [Eurekalert report from the American Journal of Psychiatry ]

April 1

  1. Effect of Ambient Air Pollution on Pulmonary Exacerbations and Lung Function in Cystic Fibrosis. Am. J. Respir. Crit. Care Med. 2004; 169: 816-821.
  2. Prospective Study of Acetaminophen Use and Newly Diagnosed Asthma among Women. Am. J. Respir. Crit. Care Med. 2004; 169: 836-841.
  3. Fracture Risk Associated with Inhaled Corticosteroid Use in Chronic Obstructive Pulmonary Disease. Am. J. Respir. Crit. Care Med. 2004; 169: 855-859.
  4. Survival of Children with Sickle Cell Disease. Blood prepublished online DOI 10.1182/ [Eurekalert]
  5. Hematopoetic stem cell transplantation for solid tumors in Europe.Ann Oncol 15: 653-660. [Survey reports fall in stem cell transplants for breast cancer, Eurekalert]
  6. Guidelines for Preventing Health-Care--Associated Pneumonia, 2003 Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee. MMWR March 26, 2004 / 53(RR03);1-36
  7. The Mortality Risk of Elevated Serum Transferrin Saturation and Consumption of Dietary Iron. Ann Fam Med 2004 2: 139-144.
  8. Small (2-cm) Breast Cancer Treated with US-guided Radiofrequency Ablation: Feasibility Study. Radiology published online.
  9. Left Cardiac Sympathetic Denervation in the Management of High-Risk Patients Affected by the Long-QT Syndrome. Circulation 2004: published online before print.[Eurekaert: Surgery cuts cardiac arrests among those with rare heart disorder]
  10. Excess Body Weight Linked To Formation Of Uric Acid Kidney Stones,[Science Daily in the April issue of Kidney International]
  11. Erectile dysfunction has devastating effect on morale. Impact of erectile dysfunction and its subsequent treatment with sildenafil: qualitative study - BMJ Online First [Eurekalert