Recent reports in Science and Medicine for June 2003

Some of these links are very transient and may expire within days of posting. Some may require prior registration. Check-in and view frequently to avoid missing great news items. I welcome any suggested articles. (email link).

June 30

  1. Improving the Quality of Care — Can We Practice What We Preach? Steinberg EP, et al. N Engl J Med 2003; 348:2681-2683
  2. The Quality of Health Care Delivered to Adults in the United States. McGlynn EA, et al. N Engl J Med 2003; 348:2635-2645 .
  3. Child survival series Where and why are 10 million children dying every year? Black RE, et al. Lancet 2003; 361: 2226-34
  4. § Residents' Suggestions for Reducing Errors in Teaching Hospitals Volpp KGM and Grande D. N Eng J Med 2003; 348:851-855 (per Dr. Velasco)

June 27

  1. FDA Approves First Biologic for Allergy-Related Asthma (FDA news release)
  2. Adherence to a Mediterranean Diet and Survival in a Greek Population. Trichopoulou A,m et al. N Engl J Med 2003; 348:2599-2608
  3. A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma.. Richardson PG, et al.N Engl J Med 2003; 348:2609-2617
  4. Outpatient Oral Prednisone after Emergency Treatment of Chronic Obstructive Pulmonary Disease Aaron SD, et al. N Eng J Med 2003; 348:2618-2625

Friday Specials - Basic Science, CME, Special interest items:

  1. Molecular 'Piggyback Ride' Carries Alzheimer’s Protein Into Brain ScienceDaily report of July 1 issue of Nature Medicine.
  2. In Memoriam: Arthur C. Guyton, MD: 1919–2003. John D. Hall Circulation 2003 107: 2990 - 2992, [Full Text]
  3. Barriers to IT Adoption by Hospitals Slowly Starting to Fall (Medscape report)
  4. Medscape CME — The T Lymphocyte in Food-Allergy Disorders: Current Opinion in Allergy and Clinical Immunology

June 26

  1. The Influence of Finasteride on the Development of Prostate Cancer Thompson IM. Published at www.nejm.org June 24, 2003 (10.1056/NEJMoa030660)
  2. Myopericarditis Following Smallpox Vaccination Among Vaccinia-Naive US Military Personnel Halsell JS, et al. JAMA. 2003;289:3283-3289.
  3. Focal and Generalized Folliculitis Following Smallpox Vaccination Among Vaccinia-Naive Recipients Talbot TR, et al. JAMA. 2003;289:3290-3294.
  4. Response to Smallpox Vaccine in Persons Immunized in the Distant Past Frey SE, et al. JAMA. 2003;289:3295-3299.
  5. Smallpox Immunization in the 21st Century: The Old and the New Wright ME and Fauci AS. JAMA. 2003;289:3306-3308.
  6. US Military Smallpox Vaccination Program Experience Grabenstein JD and Winkenwerder W. JAMA. 2003;289:3278-3282.
  7. Renal Insufficiency in the Absence of Albuminuria and Retinopathy Among Adults With Type 2 Diabetes Mellitus. Kramer HJ, et al.JAMA.  2003;289:3273-3277.
  8. Influence of Estrogen Plus Progestin on Breast Cancer and Mammography in Healthy Postmenopausal Women: The Women's Health Initiative Randomized Trial. Chlebowski RT, et al.JAMA.  2003;289:3243-3253.

June 25

  1. Reverse CPR: A Pilot Study of CPR in the Prone Position. Mazer SP, et al, "" Resuscitation2003;57: 79-285 (journal NOT online) [ScienceDaily news release].
  2. Neural correlates of interindividual differences in the subjective experience of pain Coghill RC et al. PNAS 2003, 10.1073/pnas.1430684100 . Brain Imaging Confirms That People Feel Pain Differently (Science Daily news release).
  3. Racial Differences in Outcome in the Multicenter UnSustained Tachycardia Trial (MUSTT). A Comparison of Whites Versus Blacks. Russo AM, et al. Circulation 2003: published online before print June 23, 2003,

June 24

  1. Outcome of primary angioplasty for acute myocardial infarction during routine duty hours versus during off-hours. Henriques JPS, and others. JACC 2003; 41:2138-2142 [Medscape report]
  2. AMA News release: AMA says use of stem cells for biomedical research is consistent with medical ethics
  3. Staging of Non–Small-Cell Lung Cancer with Integrated Positron-Emission Tomography and Computed Tomography. Lardinois D, and others N Eng J Med 2003;348:2500-2507.
  4. Clinical review: Diagnosis and management of intestinal ischaemic disorders Sreenarasimhaiah J , BMJ   2003;326:1372-1376 (21 June)
  5. Anecdotes as evidence. Aronson JK. BMJ 2003; 326: 1346.

June 23

  1. COMMENTARIES: Results of ALLHAT: Is This the Final Answer Regarding Initial Antihypertensive Drug Therapy? Marvin Moser Arch Intern Med. 2003;163:1269-1273.
  2. Leisure Activities and the Risk of Dementia in the Elderly. Verghese J, and others. N Engl J Med.2003; 348:2508-2516

JUNE 20

  1. FDA News June 17, 2003. First Nasal Mist Flu Vaccine Approved
  2. FDA Talk Paper June 19, 2003 FDA Statement Regarding the Anti-Depressant Paxil for Pediatric Population
  3. A Meta-analysis of the Efficacy of Second-Generation Antipsychotics. Davis JM and others. Arch Gen Psychiatry.  2003;60:553-564.
  4. Duration of Prophylaxis Against Venous Thromboembolism With Fondaparinux After Hip Fracture Surgery: A Multicenter, Randomized, Placebo-Controlled, Double-blind Study Eriksson BI and Lassen MR. Arch Intern Med. 2003;163:1337-1342.
  5. of C-Reactive Protein in Cardiovascular Risk Prediction: The Rotterdam Study. van der Meer IM, and others. Arch Intern Med. 2003;163:1323-1328.
  6. The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim. Chen CR, and othersJ. Clin. Invest. 111 :1897-1904 (2003).
  7. Heterologous immunity provides a potent barrier to transplantation tolerance Adams AB, and others. J Clin Invest 2003 111: 1887-1895.

FRIDAY SPECIAL NEWS REPORTS

  1. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever.Mongkolsapaya J, et al. Nature Medicine; Published online: 15 June 2003, doi:10.1038/nm887
  2. Increased Risk of Late Posttraumatic Seizures Associated With Inheritance of APOE 4Allele Diaz-Arrastia R, and others. Arch Neurol. 2003;60:818-822.
  3. American Diabetes Association's 63rd Annual Scientific Sessions.
  4. Intravenous Infusions Of Human Umbilical Cord Blood Stem Cells Benefit Rodents With ALS, Spinal Cord Injury (Science Daily news report)
  5. Mayo Clinic finds key digestive role for 'silent killer' (Published in PNAS) [Mayo clinc,Eurekalert and Science Daily news release)
  6. Original sin and dengue fever: T-cell activation and apoptosis contribute to pathogenesis of dengue fever (The Scientist news report) (Science link for subscribers)
  7. Commentary: Tolerance: Of mice and men. David H. Sachs. J. Clin. Invest. 111 :1819-1821 (2003). (Abstract Little is known about the effect of an individual’s immune history on his or her response to an allogeneic tissue transplant. An important study now reveals that individuals harboring virally-induced memory T cells that are cross reactive with donor alloantigen are resistant to conventional strategies designed to induce transplant tolerance.)
  8. Gut response: A bio-containable genetically modified organism promises hope for sufferers of inflammatory bowel disease (The Scientist news release)
  9. Institute of Medicine Report: Hidden Costs, Value Lost: Uninsurance in America (Executive Summary)
  10. Medscape CME: Management of Adult Obesity. L Bevoni

June 19

  1. Restricted Activity and Functional Decline Among Community-Living Older Persons. Gill TM, et al. Arch Intern Med.  2003;163:1317-1322.
  2. A Ripe Old Age (Editorial) Hadler, NM. Arch Intern Med.  2003;163:1261-1262.
  3. Diagnostic Strategies for Excluding Pulmonary Embolism in Clinical Outcome Studies. A Systematic Review. Kruip MJHA, and others. Ann Intern Med. 2003;138:941–951.
  4. Glimepiride Combined with Morning Insulin Glargine, Bedtime Neutral Protamine Hagedorn Insulin, or Bedtime Insulin Glargine in Patients with Type 2 Diabetes. A Randomized, Controlled Trial. Fritsche A, and others.Ann Intern Med. 2003;138:952–959.
  5. Cost-Effectiveness of Vaccination against Invasive Pneumococcal Disease among People 50 through 64 Years of Age: Role of Comorbid Conditions and Race. Sisk J.E, and others. Ann Intern Med. 2003;138:960–968.
  6. Editorials: Improving Patient Care.  Sox HC. Ann Intern Med. 2003;138:996.
  7. Patient Safety and the Reliability of Health Care Systems. Barach P  and . Berwick DM Ann Intern Med. 2003;138:997–998.
  8. Long-Term Effects of Inhaled Corticosteroids on FEV 1in Patients with Chronic Obstructive Pulmonary Disease A Meta-Analysis Highland KB and others. Ann Intern Med. 2003;138:969-973.
  9. Secondary prevention with folic acid: effects on clinical outcomes. Liem A, and others. JACC 2003: 41: 2105-2113.:
  10. Distal Myocardial Protection During Percutaneous Coronary Intervention With an Intracoronary ß-Blocker Wang FW, and others. Circulation 2003 107: 2914 - 2919.

June 18

  1. Effects of Treating Depression and Low Perceived Social Support on Clinical Events After Myocardial Infarction. The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. Writing Committee for the ENRICHD Investigators. JAMA.  2003;289:3106-3116.
  2. The Epidemiology of Major Depressive Disorder: Results From the National Comorbidity Survey Replication (NCS-R) Kessler RC, and others. JAMA.  2003;289:3095-3105.
  3. Cost of Lost Productive Work Time Among US Workers With Depression Stewart WF, and others. JAMA.  2003;289:3135-3144.
  4. Visceral Adipose Tissue Cutoffs Associated With Metabolic Risk Factors for Coronary Heart Disease in Women. Nicklas BJ, et al. Diabetes Care 2003 26: 1413-1420.
  5. Cost Effectiveness of Statin Therapy for the Primary Prevention of Major Coronary Events in Individuals With Type 2 Diabetes. Brandle M, et al.Diabetes Care 2003 26: 1796-1801.
  6. Treating Hypertension in Diabetic Nephropathy. Tomlinson JW, et al. Diabetes Care 2003 26: 1802-1805.  
  7. Identification and Management of Diabetic Nephropathy in the Diabetes Clinic. Craig KJ, et al.Diabetes Care 2003 26: 1806-1811.
  8. Risk of Ischemic Stroke Among Users of the Oral Contraceptive Pill. The Melbourne Risk Factor Study (MERFS) Group. Siritho S, and others. Stroke published online June 12, 2003,

June 17

  1. Prognostic Value of Ambulatory Blood-Pressure Recordings in Patients with Treated Hypertension Clement DL, et al. N Engl J Med 2003; 348:2407-2415
  2. Volume Expansion With Albumin Decreases Mortality After Coronary Artery Bypass Graft Surgery. Sedrakyan A, et al. Chest 2003 123: 1853-1857.
  3. A Comparison of the Effects of Salbutamol and Ipratropium Bromide on Exercise Endurance in Patients With COPD. Oga T, et al.
    Chest 2003 123: 1810-1816.
  4. Cardiac Troponin T Monitoring Identifies High-Risk Group of Normotensive Patients With Acute Pulmonary Embolism. Pruszczyk P, et al. Chest 2003 123: 1947-1952.
  5. Accepting Critically Ill Transfer Patients: Adverse Effect on a Referral Center's Outcome and Benchmark Measures. Rosenberg AL, et al. Ann Intern Med. 2003;138:882–890.

June 16

  1. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial Heart Protection Study Collaborative Group. Lancet 2003; 361: 2005-16. [Statin Therapy Should Be Considered for All Diabetics at CVD Risk  Medscape CME]
  2. Obesity in general elective surgery. Dindo D, et al. Lancet 2003; 361: 2032-35
  3. Editorial SSRIs: suicide risk and withdrawal Lancet Volume 361, Number 9374; 14 June 2003
  4. Effect of fluvastatin on cardiac outcomes in renal transplant recipients: a multicentre, randomised, placebo-controlled trial. Holdaas H, et al. Lancet 2003; 361: 2024-31. Published online June 3, 2003
  5. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Vivekananthan DP, et al. Lancet 2003; 361: 2017-23 .
  6. Sex Differences in First-Ever Acute Stroke. Roquer J, and others.Stroke published online June 12, 2003.

June 13

  1. Volume Expansion With Albumin Decreases Mortality After Coronary Artery Bypass Graft Surgery. Sedrakyan A, et al. Chest 2003 123: 1853-1857.
  2. A Comparison of the Effects of Salbutamol and Ipratropium Bromide on Exercise Endurance in Patients With COPD. Oga T, et al.
    Chest 2003 123: 1810-1816.
  3. Cardiac Troponin T Monitoring Identifies High-Risk Group of Normotensive Patients With Acute Pulmonary Embolism. Pruszczyk P, et al. Chest 2003 123: 1947-1952.

FRIDAY SPECIAL REPORTS

  1. Physicians perceive health care cost savings line pockets of insurance companies . At a time when health care costs are rising, a new study led by a University of Michigan Health System doctor finds that many physicians think their efforts at saving money don't directly impact patients. American Journal of Managed Care (no online contents; journal carried by PHD Library). .[Eurekalert news report]
  2. TRB3 may promote development of type 2 diabetes by interfering with Akt phosphorylation [The Scientist report on TRB3: A tribbles Homolog That Inhibits Akt/PKB Activation by Insulin in Liver. Du K, et al Scinece 2003; 300:1574-1577 - subscribers link)
  3. Medscape CME - Advances in Therapies for Stress Urinary Incontinence -- Focus on the Female Patient Author: Donald R. Ostergard, MD, FACOG
  4. Coincidence of synteny breakpoints with malignancy-related deletions on human chromosome 3 Kost-Alimova M, et al. PNAS 2003 100: 6622-6627; published online before print (The finding contradicts the "textbook model" of metastasis, which says that cancer cells spread relatively late in the process only after they have undergone massive genetic changes. The new finding may explain why some patients develop tumors in bones or other organs decades after having the original tumor removed)
  5. Safety of Seroxat (paroxetine) in children and adolescents under 18 years - contraindication in the treatment of depressive illness - Epinet message from Professor G Duff, Chairman of Committee on Safety of Medicines (June 10, 2003 statement from Medicine and Healathcare Products Regulations Agency - UK) ( Medscape: UK Govt Warns on Paroxetine Use in Under-18 Patients) (and BBC news report)
  6. Biofilms in cystic fibrosis: Analysis of Pseudomonas extracellular matrix sheds light on chronic lung infections (The Scientist summary of June 9 Proceedings of the National Academy of Sciences paper:(PNAS , DOI:10.1073/pnas.1231792100)

 

June 12

  1. Aspirin and Ticlopidine for Prevention of Recurrent Stroke in Black Patients: A Randomized Trial. Gorelick PB, et al. JAMA.  2003;289:2947-2957.
  2. Antibody Response to Chlamydial Heat Shock Protein 60 Is Strongly Associated With Acute Coronary Syndromes. Biasucci LM, et al. Circulation 2003: published online before print June 9, 2003 [A Bacterial Inflammatory Protein Linked With Heart Disease Risk Science Daily news]
  3. Prevalence of Complicated Carotid Atheroma as Detected by Magnetic Resonance Direct Thrombus Imaging in Patients With Suspected Carotid Artery Stenosis and Previous Acute Cerebral Ischemia Murphy RE, et al. Circulation 2003: published online before print June 9, 2003,
  4. Perioperative Cardiac Assessment for Noncardiac Surgery: Eight Steps to the Best Possible Outcome Mukherjee D and Eagle KA. Circulation 2003 107: 2771 - 2774,  
  5. Coronary Endothelial Dysfunction Is Associated With an Increased Risk of Cerebrovascular Events. Targonski PV, et al. Circulation. 2003;107:2805.
  6. Improving Guideline Adherence: A Randomized Trial Evaluating Strategies to Increase ß-Blocker Use in Heart Failure. Ansari M, et al. Circulation 2003 107: 2799 - 2804

June 11

  1. Test-and-treat strategy for H. pylori modestly effective, but not cost saving. Allison JE, et al. Arch Intern Med 2003;163:1165-1171.
  2. Effects of a 16-Month Randomized Controlled Exercise Trial on Body Weight and Composition in Young, Overweight Men and Women: The Midwest Exercise Trial. Donnelly JE, et al. Arch Intern Med. 2003;163:1343-1350.
  3. Percutaneous Endoscopic Gastrostomy Does Not Prolong Survival in Patients With Dementia Murphy LM and Lipman TO. Arch Intern Med. 2003;163:1351-1353.
  4. Continuity of Care and Recognition of Diabetes, Hypertension, and Hypercholesterolemia Koopman RJ, et al. Arch Intern Med. 2003;163:1357-1361.
  5. Reduction of Out-of-Hospital Symptomatic Venous Thromboembolism by Extended Thromboprophylaxis With Low-Molecular-Weight Heparin Following Elective Hip Arthroplasty: A Systematic Review O'Donnell M, et al. Arch Intern Med. 2003;163:1362-1366.
  6. Alcohol Drinking Patterns and Risk of Type 2 Diabetes Mellitus Among Younger Women Wannamethee SG, et al. Arch Intern Med. 2003;163:1329-1336.

June 10

  1. Homicide and suicide risks associated with firearms in the home: A national case-control study. Wiebe DJ. Ann Emerg Med. 2003; 41:771-782.
  2. Patient Safety Events During Pediatric Hospitalizations, Miller MR, et al. Pediatrics 2003; 111: 1358-1366.
  3. Clinical Prevention of Sudden Cardiac Death by n-3 Polyunsaturated Fatty Acids and Mechanism of Prevention of Arrhythmias by n-3 Fish Oils Leaf A, et al.Circulation 107: 2646-2652,
  4. Editorials - The Fish Story: A Diet–Heart Hypothesis With Clinical Implications: n-3 Polyunsaturated Fatty Acids, Myocardial Vulnerability, and Sudden Death David S. Siscovick, Circulation. 2003;107:2632

June 9

  1. Smoking During Pregnancy and Newborn Neurobehavior. Law K, et al. Pediatrics 2003; 111: 1318-1323. (News release Brown University: Nicotine changes newborn behavior in ways similar to heroin and crack )
  2. Changes in Smoking Status Affect Women More than Men: Results of the Lung Health Study. Connett JE, et al. Am. J. Epidemiol. 2003 157: 973-979.
  3. Regression of Microalbuminuria in Type 1 Diabetes. Perkins BA, et al. N Engl J Med 2003; 348:2285-2293
  4. Genomic Medicine: Breast and Ovarian Cancer. WoosterR and Weber BL. N Engl J Med 2003;. 348:2339-2347
  5. Puberty and Genetic Susceptibility to Breast Cancer in a Case–Control Study in Twins.Hamilton AS and Mack TM. N Engl J Med 2003;348:2313-2322.
  6. Synchronization of Neurogenesis and Motor Neuron Specification by Direct Coupling of bHLH and Homeodomain Transcription Factors. Lee SKand Pfaff SL.Neuron, Vol 38, 731-745, 5 June 2003 [Science Daily report: Motor Nerve Cell 'Factory' Findings May Elicit Treatments For Spinal Cord Injury, Disease ]

June 6

  1. Rapid Magnetic Resonance Imaging vs Radiographs for Patients With Low Back Pain: A Randomized Controlled Trial. Jarvik JG, et al. JAMA. 2003;289:2810-2818.
  2. Effects of Rofecoxib or Naproxen vs Placebo on Alzheimer Disease Progression: A Randomized Controlled Trial. Aisen PS, et al. JAMA. 2003;289:2819-2826.
  3. Paroxetine Controlled Release in the Treatment of Menopausal Hot Flashes: A Randomized Controlled Trial. Stearns V, et al. JAMA. 2003;289:2827-2834..

Friday Special Reports!

  1. Studies of liver transplant patients off anti-rejection drugs have altered cell profile. Results reported in American Journal of Transplantation (unavailable online) and at American Transplant Congress (Eurekalert news release)
  2. A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen Xue D, et al. PNAS published June 3, 2003, 10.1073/pnas.0832411100 [HHMI news release]  
  3. Monoclonal antibody achieves best results for chronic lymphocytic leukemia. Presented at the annual meeting of the American Society of Clinical Oncology (Eurekalert news release)
  4. First effective drug for sleep disorder identified (presented this week at the annual meeting of the Associated Professional Sleep Societies) - Eurekalert news report
  5. Researchers Discover Possible Diagnosis, Treatment, Vaccine For Mad Cow, Prion Diseases (Science Daily and BBC news report of Nature Medicine study not available to non-subscribers)

June 5

  1. Spinal Manipulative Therapy for Low Back Pain. A Meta-Analysis of Effectiveness Relative to Other Therapies Assendelft WJJ, et al. Ann Intern Med. 2003;138:871–881.
  2. A Review of the Evidence for the Effectiveness, Safety, and Cost of Acupuncture, Massage Therapy, and Spinal Manipulation for Back Pain. Cherkin DC, et al. Ann Intern Med. 2003;138:898–906.
  3. Reviews: The Epidemiology of "Asymptomatic" Left Ventricular Systolic Dysfunction: Implications for Screening. Wang T.J, et al.Ann Intern Med. 2003;138:907–916.
  4. Pharmacotherapy for Heart Failure in Patients with Renal Insufficiency Shlipak M.G. Ann Intern Med. 2003;138:917–924.
  5. Clinical Guidelines: Screening for Dementia: Recommendation and Rationale U.S. Preventive Services Task Force Ann Intern Med. 2003;138:925–926.
  6. Screening for Dementia in Primary Care: A Summary of the Evidence for the U.S. Preventive Services Task Force. Boustani M, et al. Ann Intern Med. 2003;138:927–937.
  7. Editorials: Applying Evidence to Patient Care: From Black and White to Shades of Grey F.A. McAlister Ann Intern Med. 2003;138:938–939.

June 4

  1. Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA. Amieva M R, et al. Science May 30 2003: 1430-1434 (subscribers). [TheScientist news report]
  2. Effect of fluvastatin on cardiac outcomes in renal transplant recipients: a multicentre, randomised, placebo-controlled trial Holdaas H, et al. Lancet 2003; published online June 3.
  3. Effect of enalapril on 12-year survival and life expectancy in patients with left ventricular systolic dysfunction: a follow-up study. Jong P, et al. Lancet 2003; 361: 1843-48
  4. Effect of a diabetic environment in utero on predisposition to type 2 diabetes. Sobngwi E, et al. Lancet 2003; 361: 1861-65
  5. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial KalliomäkiM, et al.Lancet 2003:361: Research Letters
  6. Association between tuberculosis and a polymorphic NF B binding site in the interferon gene  Rossouw M, et al.Lancet 2003:361: Research Letters

June 3

  1. Nanog: A New Recruit to the Embryonic Stem Cell Orchestra. Cavaleri F and Schöler HR. Cell 2003;113, 551-552.(subscription required; not in PHS Library) {Stem cell 'immortality' gene found.NewScientist.com news service and Science Daily aand the institutional news release}
  2. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. Lexchin J, et al. BMJ 2003;326:1167-1170..[Research funded by drug companies is 'biased' [NewScientist.com news service and Medscape commentary]
  3. Telomere maintenance and disease. Wong JMY and Collins KLancet 2003:361: Lancet 2003:361 Research Letters
  4. Assessment and management of cancer-related fatigue in adults. Ahlber K , et al. Lancet 2003:361: Research Letters
  5. Heat shock proteins as regulators of the immune response. Pockley AG Lancet 2003:361: Research Letters
  6. B-type natriuretic peptide in cardiovascular disease.De Lemos JA, et al.Lancet 2003:361: Research Letters

June 2

  1. Nanog: A New Recruit to the Embryonic Stem Cell Orchestra. Cavaleri F and Schöler HR. Cell 2003;113, 551-552.(subscription required; not in PHS Library) {Stem cell 'immortality' gene found.NewScientist.com news service and Science Daily aand the institutional news release}
  2. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. Lexchin J, et al. BMJ 2003;326:1167-1170..[Research funded by drug companies is 'biased' [NewScientist.com news service]
  3. Telomere maintenance and disease. Wong JMY and Collins KLancet 2003:361: Lancet 2003:361 Research Letters
  4. Assessment and management of cancer-related fatigue in adults. Ahlber K , et al. Lancet 2003:361: Research Letters
  5. Heat shock proteins as regulators of the immune response. Pockley AG Lancet 2003:361: Research Letters
  6. B-type natriuretic peptide in cardiovascular disease.De Lemos JA, et al.Lancet 2003:361: Research Letters