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Recent reports in Science and Medicine for November 2004

Some of these links are very transient and may expire within days of posting. Some may require prior registration. Check-in and view frequently to avoid missing great news items. I welcome any suggested articles. (email link). "§" indicates a recommended article.

 November 30                  
  1. Non-steroidal anti-inflammatory drugs, including cyclo-oxygenase-2 inhibitors, in osteoarthritic knee pain: meta-analysis of randomised placebo controlled trials. BMJ, online release doi:10.1136.
  2. Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2. A Double-Blind, Placebo-Controlled Study of Extended-Release Niacin on Atherosclerosis Progression in Secondary Prevention Patients Treated With Statins. Circulation 2004 11;CIR.0000148955.19792.8D.
  3. Systolic Blood Pressure During Recovery From Exercise and the Risk of Acute Myocardial Infarction in Middle-Aged Men. Hypertension 2004 44: 820-825, doi:10.1161/01.HYP.0000148460.95060.f2
  4. BMJ 27 November 2004 (Vol 329, No 7477)
  5. New England Journal of Medicine  Volume 351 November 25, 2004 Number 22
 November 29                  
  1. A 24-year follow-up of body mass index and cerebral atrophy. Neurology 2004 63: 1876-1881.
  2. Long-term obesity is linked to loss of brain tissue. Neurology 2004 63: E19-20.[ScienceDaily report]
  3. A comprehensive examination of health conditions associated with obesity in older adults. Am J Preventive Medicine. 2004; 27: 385-390 (via Science Direct). [Eurekalert : Obesity tied to increased risk for dozens of conditions]
  4. IDSA Statement: CID Recommendation for Vaccinating Adolescents Against Whooping Cough
  5. Chronic Back Pain Is Associated with Decreased Prefrontal and Thalamic Gray Matter Density. J. Neurosci. 2004 24: 10410-10415. [ScienceDaily]
  6. JAMA. Vol. 292 No. 20, pp. 2439-2540, November 24, 2004
November 24-26                    

Holiday Reading - Basic Science and general interest articles

  1. FDA News: Approval of Tarceva (erlotinib) for the most common type of lung cancer: Survival benefit
  2. FDA Talk Paper: Black Box Warning Added Concerning Long-Term Use of Depo-Provera Contraceptive Injection
  3. Malnutrition at Age 3 Years and Externalizing Behavior Problems at Ages 8, 11, and 17 Years. Am J Psychiatry 2004 161: 2005-2013. [ScienceDaily: Malnutrition In Early Years Leads To Low IQ And Later Antisocial Behavior]
  4. COX-2 Derived Prostacyclin Confers Atheroprotection on Female Mice. Science 2004 published online 18 November 2004.[Hormaones and the heart: ScienceNow]
  5. Theobromine inhibits sensory nerve activation and cough. FASEB J. published Nov 17, 2004. [Eurekalert]
 November 23                  
  1. CMAJ November 9 2004, Volume 171, Issue 10
  2. MMWR: Prevalence of Overweight and Obesity Among Adults with Diagnosed Diabetes --- United States, 1988--1994 and 1999--2002.
  3. §  Serologic Evidence for Exposure to Simian Virus 40 in North American Zoo Workers. JID 2004;190:000 online.
  4. §  Right Ventricular Enlargement on Chest Computed Tomography: A Predictor of Early Death in Acute Pulmonary Embolism. Circulation 2004 110: 3276 - 3280. [Medscape review]
 November 22                  
  1. Management of Brown Recluse Spider Bites in Primary Care. J Am Board Fam Prac 2004; 17:347-352 .
  2. Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy. J. Clin. Invest. 114:1504-1511. [Eurekalert: Muscle loss from space travel, prolonged inactivity linked to two genes]
  3. New England Journal of Medicine Volume 351   November 18, 2004  Number 21
November 19                    

Weekend Reading - Basic Science and general interest articles

  1. Human Prion Protein with Valine 129 Prevents Expression of Variant CJD Phenotype. Science Nov 11, 2004 Published online 10.1126/science. (Science Express Reports ) [New Scientist - Humans may get different forms of BSE ]
  2. Neuroglial activation and neuroinflammation in the brain of patients with autism (p NA) Annals of Neurology published Online: 15 Nov 2004 [Autism Associated With Brain Inflammation ScienceNow]
  3. §  The AMPA Receptor Subunits GluR-A and GluR-B Reciprocally Modulate Spinal Synaptic Plasticity and Inflammatory Pain. Neuron 2004; 44: 637-650.(How receptors govern inflammatory pain)
  4. FDA Reports
    • FDA Reports and Information: Mifeprex (mifepristone) revision of the BOXED WARNING and WARNINGS sections, the MEDICATION GUIDE and PATIENT AGREEMENT of the Prescribing Information to describe serious and sometimes fatal infections and bleeding that may occur following the use of Mifeprex.[Medscape]
    • FDA Statement: Vioxx and Recent Allegations and the Agency's Continued Commitment to Sound Science and Peer Review
    • FDA Talk Paper: Black Box Warning Added Concerning Long-Term Use of Depo-Provera Contraceptive Injection
    • FDA News: FDA Announces New Initiative to Protect the U.S. Drug Supply Through the Use Of Radiofrequency Identification Technology
    • FDA Proposed Medication Guide:About Using Antidepressants in Children or Teenagers
    • FDA Safety Labeling Changes: Actos, Geodon, Prozac, and Others [Medscape]
      • Pioglitazone (Actos) May be Linked to Cardiac Adverse Events in Patients With Uncontrolled Diabetes and Systolic Heart Failure
      • Ziprasidone (Geodon) May Be Associated With Risk of Hyperglycemia, Diabetes
      • Paroxetine (Pexeva), Fluoxetine (Prozac), and Sertraline (Zoloft) May Cause Worsening of Depression/Suicidality
    • FDA Approvals: Oxaliplatin (Eloxatin) for Use With 5-FU/LV in Adjuvant Treatment of Stage III Colon Cancer; Orphan Drug Status for Cloretazine (VNP40101M) in Acute Myelogenous Leukemia, , Orphan Drug Status for BAY 43-9006 in Metastatic Renal Cell Carcinoma, Device (2000i) Delivers Breathing Gases in Neonatal and Pediatric Patients, Medroxyprogesterone Acetate Available in Prefilled Single-Dose Syringes.[Medscape]
  5. MEDSCAPE: FDA Accused of Mishandling Flu Vaccine Oversight
  6. §  Postprocessing In Vitro Digestion Challenge To Evaluate Survival of Escherichia coli O157:H7 in Fermented Dry Sausages. Appl. Environ. Microbiol. 2004. 70: 6637-6642. (E.coli in Dried Sausage Able to Withstand Digestion Process)
 November 18                  
  1. JAMA Vol. 292 No. 19, pp. 2311-2430, November 17, 2004
  2. §  Stem cells: science, policy, and ethics. J. Clin. Invest. 114:1364-1370
  3. Peanut allergy: Recurrence and its management. J Allergy Clin Immunology 2004; 114. [Eurekalert & Science Daily: Monthly ingestion appears to boost peanut tolerance]
  4. The association between cardiorespiratory fitness and C-reactive protein in subjects with the metabolic syndrome. JACC 2004; 44:2003-7. (access through Cardiocource) [Medscape review]
 November 17                  
  1. Genetic Manipulation of Telomerase in HIV-Specific CD8+ T Cells: Enhanced Antiviral Functions Accompany the Increased Proliferative Potential and Telomere Length Stabilization. J Immunol 2004 173: 6303-6311.[Eurekalert]
  2. Acute Effects of Ozone on Mortality from the "Air Pollution and Health: A European Approach" Project. Am. J. Respir. Crit. Care Med. 2004; 170: 1080-1087.
  3. Syncope Evaluation in the Emergency Department Study (SEEDS). A Multidisciplinary Approach to Syncope Management. Published online before print November 9, 2004; Circulation 2004, doi:10.1161/01.
  4. The Prevalence of Gastroesophageal Reflux Disease in Adult Asthmatics. Chest 2004 126: 1490-1494.
  5. Annals of Internal Medicine 16 November 2004 Volume 141 Issue 10
    • §  Advanced Age, Anticoagulation Intensity, and Risk for Intracranial Hemorrhage among Patients Taking Warfarin for Atrial Fibrillation. [Abstract]
    • Comparison of Endoscopic Ultrasonography and Multidetector Computed Tomography for Detecting and Staging Pancreatic Cancer [Abstract]
    • §  Taking Glucocorticoids by Prescription Is Associated with Subsequent Cardiovascular Disease [Abstract]
    • §  Improving Patient Care Measuring the Quality of Physician Practice by Using Clinical Vignettes: A Prospective Validation Study [Abstract]
    • Better Reporting of Harms in Randomized Trials: An Extension of the CONSORT Statement. [Abstract]
    • Update in Rheumatology [Full Text]
    • Update on the Health Disparities Literature. [Full Text]
    • Reviews The Physiologic Basis of High-Altitude Diseases. [Full Text]
    • Editorials: Back to the Future: Clinical Vignettes and the Measurement of Physician Performance
    • Editorials: Inequality in Health Care: Unjust, Inhumane, and Unattended!
    • On Being a Doctor Medicine in the Family. [Full Text]
    • Current Clinical Issues  The Health Care Revival in Iraq. [Full Text]
 November 16                  
  1. The Lancet Volume 364, Number 9447     13 November 2004
    • Early online publication: The whole truth and nothing but the truth? The research that Philip Morris did not want you to see
    • § Early online publication: Risk of cardiovascular events and rofecoxib: cumulative meta-analysis
    • Comment: Vioxx, the implosion of Merck, and aftershocks at the FDA
    • Comment: The war in Iraq: civilian casualties, political responsibilities
    • § Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial . GlaxoSmithKline HPV Vaccine Study Group [Eurekalert]
    • Surgical excision vs Mohs' micrographic surgery for basal-cell carcinoma of the face: randomised controlled trial  [Summary] 
    • The United Kingdom Infantile Spasms Study comparing vigabatrin with prednisolone or tetracosactide at 14 days: a multicentre, randomised controlled trial  [Summary] 
    • Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist  [Summary] 
    • § Uncoupling proteins in human heart  [Summary]  [Medscape]
  2. Archives of Internal Medicine Vol. 164 No. 20, pp. 2191-2292, November 8, 2004
 November 15                  
  1. Impact of Prophylactic Postoperative -Blockade on Post-Cardiothoracic Surgery Length of Stay and Atrial Fibrillation. Annals Pharmacotherapy Published online, 26 October 2004, www.theannals.com, DOI 10.1345/aph.1E310. [ Eurekalert: Beta blockers after cardiac surgery reduce length of stay and complications]
  2. §  Risks of clinically significant upper gastrointestinal events with etodolac and naproxen: A historical cohort analysis. Gastroenterology November 2004 • Volume 127 • Number 5 [Eurekalert report]
  3. Evidence for an Association between Metabolic Cardiovascular Syndrome and Coronary and Aortic Calcification among Women with Polycystic Ovary Syndrome. J Clin Endocrinol Metab 2004 89: 5454-5461.[Medscape: Study links polycystic ovary syndrome with early vascular changes of heart disease]
  4. Are family meal patterns associated with disordered eating behaviors among adolescents? Neumark-Sztainer D, Wall M, Story M, Fulkerson JA. J Adol Health 2004; 35: 350-359.[Eurekalet: Regular family meals promote healthy eating habits]
  5. §  Annals of Internal Medicine Early Release Article: Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality.
  6. New England Journal of Medicine Volume 351  November 11, 2004  Number 20
November 12                    

Weekend Reading - Basic Science and general interest articles

  1. FDA Statement: FDA Acts to Strengthen the Safety Program for Marketed Drugs
  2. FDA MedWatch: Humira (adalimumab) WARNINGS; include serious infections with the combined use of Humira (adalimumab) and anakinra, hypersensitivity reactions, including anaphylaxis, and hematologic events, including pancytopenia and aplastic anemia. [Medscape]
  3. § Antigen-independent memory CD8 T cells do not develop during chronic viral infection. PNAS published October 25, 2004, 10.1073/pnas [Eurekalert] Longterm immune memory cells cells do not develop during chronic viral infections.
  4. Valdecoxib Meta-Analysis Suggests Increased Cardiovascular Risk. Garret A. FitzGerald, MD, reported the findings at the American Heart Association (AHA) 2004 Scientific Sessions, said valdecoxib use was associated with a 2.19 increase in relative risk of cardiovascular events. [Medscape report]
  5. The gut microbiota as an environmental factor that regulates fat storage. PNAS  2004; 101: 15718-15723.
  6. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice. J. Clin. Invest. 2004 114: 1248-1259. [The Scientist revew]
  7. Body Mass Index in Mid-Life Is Associated With a First Stroke in Men. A Prospective Population Study Over 28 Years. Stroke published October 28, 2004.[AHA news release]
  8. Cells from babies help heal their mothers. [New Scientist]
  9. Target for Nicotine Addiction Found. [Science Now report from Science, Vol 306, Issue 5698, 1029-1032.]
  10. § New AHRQ Survey Helps Hospitals Measure and Improve Patient Safety Culture.[Survey] AHRQ Website
  11. America's Health: State Health Rankings 2004 [Complete report or Health Rankings online] (Medical News: US Health Improvements Slowing - Alarm at High Infant Mortality Rates and Obesity)
  12. Dietary -Linolenic Acid Reduces Inflammatory and Lipid Cardiovascular Risk Factors in Hypercholesterolemic Men and Women. J. Nutr. 2004 134: 2991-2997. [Eurekalert]
  13. Incidence of Metabolic Syndrome Low When Weight Is Stable. [Medscape report from American Heart Association 2004 Scientific Sessions.
 November 11                  
  1. BMJ 6 November 2004 (Vol 329, No 7474)
    • The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis. BMJ 2004;329:1067
    • Paternal age and schizophrenia: a population based cohort study. BMJ 2004;329:1070.
    • Impact of congenital colour vision deficiency on education and unintentional injuries: findings from the 1958 British birth cohort. BMJ 2004;329:1074-1075.
    • DRUG POINTS: QT interval increased after singledose of lofexidine.BMJ 2004;329:1075,
    • Preventing and treating hepatitis B infection. BMJ 2004;329:1080-108
    • § Users' guide to detecting misleading claims in clinical research reports. BMJ 2004;329:1093-1096.
    • Monitoring global health: time for new solutions.BMJ 2004;329:1096-1100.
  2. Merck's Withdrawal of Vioxx Calls the Cardiac Safety of COX-2 Inhibitors Into Question [Medscape review]
  3. § Glycemic Index and Dietary Fiber and the Risk of Type 2 Diabetes. Diabetes Care 2004 27: 2701-2706.
  4. Temporally Specific Burst in Cell Proliferation Increases Hippocampal Neurogenesis in Protracted Abstinence from Alcohol. J. Neurosci. 2004 24: 9714-9722. [Eurekalert]
  5. Interrelations Between Brachial Endothelial Function and Carotid Intima-Media Thickness in Young Adults: The Cardiovascular Risk in Young Finns Study. Circulation 2004;110:2918-2923. [AHA news]
  6. JAMA Vol. 292 No. 18, pp. 2189-2302,  November 10, 2004
 November 10                  
  1. New England Journal of Medicine Early Release:
  2. Psychiatric Correlates of Gambling in Adolescents and Young Adults Grouped by Age at Gambling Onset. Arch Gen Psychiatry. 2004;61:1116-1122.
  3. The Lancet Volume 364, Number 9446 | 06 November 2004
    • § Early online publication: Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. Jüni, and others. [§ NewScientist report]
    • Mortality before and after the 2003 invasion of Iraq: cluster sample survey. Roberts, et al.
    • Vioxx, the implosion of Merck, and aftershocks at the FDA. Horton
    • The war in Iraq: civilian casualties, political responsibilities. Horton
    • Editorial: Public-health preparedness requires more than surveillance.
    • Editorial: Warning: geography may be hazardous to your health
    • Population-based multidimensional assessment of older people in UK general practice: a cluster-randomised factorial trial. Fletcher, and others.
    • Regression of low-grade squamous intra-epithelial lesions in young women. Moscicki, and others.
    • § Atenolol in hypertension: is it a wise choice? Carlberg, and others. [ Medscape report]
    • High-dose immunoglobulin during pregnancy for recurrent neonatal haemochromatosis.Whitington, and others.
    • The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes. Gillespie,and others.
    • Uncoupling proteins in human heart. Murray, and others.
November 9                  
  1. New England Journal of Medicine Volume 351   November 4, 2004  Number 19
  2. November 2004 issue of Arthritis & Rheumatism
    • § The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. A & R 2004: 50: 3516 - 3525 [Eurekalert and Medscape]
    • Antiarthritic effect of bee venom: Inhibition of inflammation mediator generation by suppression of NF-B through interaction with the p50 subunit (3504-3515) Eurekalert
    • Cardiovascular risk factors in women with and without rheumatoid arthritis (3444-3449) , Eurekalert
    • § Measurement of erythrocyte C4d and complement receptor 1 in systemic lupus erythematosus (3596-3604) .Eurekalert
  3. § AGA News Releases Studies Address Heavily-Debated Issues Surrounding Virtual Colonoscopy
  4. Flat Colorectal Lesions in Asymptomatic Adults: Implications for Screening with CT Virtual Colonoscopy. AJR 2004; 183:1343-1347. [New Study Lays To Rest Concerns About Virtual Colonoscopy As A Screening Tool ScienceDaily ]
November 8                    
  1. JAMA. Vol. 292 No. 17, pp. 2049-2182, November 3, 2004
    • § Annual Revaccination Against Influenza and Mortality Risk in Community-Dwelling Elderly Persons. JAMA. 2004;292:2089-2095.
    • Utilization of Early Invasive Management Strategies for High-Risk Patients With Non–ST-Segment Elevation Acute Coronary Syndromes: Results From the CRUSADE Quality Improvement Initiative. JAMA. 2004;292:2096-2104.
    • Differential Genetic Effects of ESR1 Gene Polymorphisms on Osteoporosis Outcomes. JAMA. 2004;292:2105-2114.
    • § Hospitalization, Restricted Activity, and the Development of Disability Among Older Persons. JAMA. 2004;292:2115-2124.
    • Is There a Doctor in the House? . . . Or the Senate?: Physicians in US Congress, 1960-2004. JAMA. 2004;292:2125-2129.
    • Reviews: Trends in the Risks and Benefits to Patients With Cancer Participating in Phase 1 Clinical Trials. JAMA. 2004;292:2130-2140.
    • Perspectives on Care at the Close of Life: Caring for the Child With Cancer at the Close of Life: "There Are People Who Make It, and I’m Hoping I’m One of Them". JAMA. 2004;292:2141-2149.
    • § Editorials: Risks and Benefits of Phase 1 Clinical Trials Evaluating New Anticancer Agents: A Case for More Innovation.  JAMA. 2004;292:2150-2151.
  2. § Clinical outcomes in managed-care patients with coronary heart disease treated aggressively in lipid-lowering disease management clinics: The alliance study. J Am College Cardiology 2004; 44: 1772-1779. [Medscape report]. Access via ScienceDirect
  3. Alterations of Left Ventricular Myocardial Characteristics Associated With Obesity. Circulation 2004: published online before print November 1, 2004
November 5                    

New England Journal of Medicine Early Release November 3, 2004

Weekend Reading - Basic Science and general interest articles

  1. FDA News:  FDA Warns Consumers of the Dangers of Using Decorative Contact Lenses Without Proper Professional Involvement.
  2. FDA News: Qualified health claim for monounsaturated fat from olive oil and decrease in risk of coronary heart disease.
  3. FDA Approvals: Evoclin (Clindamycin Foam 1% for Acne), Norditropin NordiFlex (Premixed, Multidose, Disposable Pen for Somatropin Injection), Femtrace (Estradiol Acetate for Relief of Vasomotor Symptoms of Menopause), Hylaform Plus (Large Particle Hyaluronic Acid Gel Filler for Facial Wrinkles and Folds), and New Formulations: Donepezil (Aricept), Fexofenadine (Allegra-D), Levofloxacin (Levaquin), Famotidine (Fluxid).
  4. Global health leaders join the World Health Organization to announce accelerated efforts to improve patient safety.
  5. The Launch of the World Alliance for Patient Safety
  6. Hepcidin Regulates Iron Efflux by Binding to Ferroportin and Inducing Its Internalization. Science Published online October 28 2004; 10.1126/science.1104742. [ScienceDaily Researchers Identify How A Hormone Regulates Iron]
  7. CYP3A Variation and the Evolution of Salt-Sensitivity Variants. Am. J. Hum. Genet., 75:1059-1069, 2004. ['Broken' gene reveals evolution of salt retention and possible ties to hypertension Eurekalert ]
  8. A randomized trial of atropine regimens for treatment of moderate amblyopia in children. Ophthalmology 2004; 111: 2076-2085. [Eurekalert: New ways identified to treat 'lazy eye' in children]
  9. Enzyme linked to mania and schizophrenia impairs higher brain functions. Eurekalert report published Oct. 29 in Science.
  10. Scientists identify key mechanism in estrogen's role in preventing bone loss. Eurekalert PNAS the week of October 25.
  11. US in U-turn over Gulf war syndrome [New Scientist report from US Department of Veterans Affairs’ Research Advisory Committee on Gulf War Veterans’ Illnesses]
November 4                    
  1. Enlarged perivascular spaces are associated with cognitive function in healthy elderly men. J Neurol Neurosurg Psychiatry 2004; 75: 1519-1523. [Eurekalert]
  2. Alterations of Left Ventricular Myocardial Characteristics Associated With Obesity. Circulation 2004: published online November 1, 2004.[Medscape]
  3. Dispositional Optimism and All-Cause and Cardiovascular Mortality in a Prospective Cohort of Elderly Dutch Men and Women. Arch Gen Psychiatry. 2004;61:1126-1135.
  4. Preventing Substance Use and Disordered Eating: Initial Outcomes of the ATHENA (Athletes Targeting Healthy Exercise and Nutrition Alternatives) Program. Arch Pediatr Adolesc Med. 2004;158:1043-1049.
  5. Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: Results of a randomized double-blind trial. Gastroenterology. 2004;127:1038-1043
  6. Annals of Internal Medicine ::  2 November 2004
    • § Cost-Effectiveness of Rhythm versus Rate Control in Atrial Fibrillation. Marshall, and others
    • The Epidemiology of Severe Acute Respiratory Syndrome in the 2003 Hong Kong Epidemic: An Analysis of All 1755 Patients. Leung, and others
    • § Accuracy of Computed Tomographic Angiography and Magnetic Resonance Angiography for Diagnosing Renal Artery Stenosis. Vasbinder, and others
    • Patient Education for Colon Cancer Screening: A Randomized Trial of a Video Mailed before a Physical Examination. Zapka, and others.
    • Meta-Analysis: Angiotensin-Receptor Blockers in Chronic Heart Failure and High-Risk Acute Myocardial Infarction. Lee, and others
    • PERSPECTIVES: Is There a Role for Maintaining Sinus Rhythm in Patients with Atrial Fibrillation? Zimetbaum and Josephson
    • MEDICINE AND PUBLIC ISSUES: Weighing the Evidence for Expanding Physician Supply. Cooper
    • Testing for Hepatitis C Virus Infection Should Be Routine for Persons at Increased Risk for Infection. Alter, Seeff, and others
    • The Meaning of the U.S. Preventive Services Task Force Grade I Recommendation: Screening for Hepatitis C Virus Infection. Calonge and Randhawa
    • EDITORIALS: To Be or Not To Be in Normal Sinus Rhythm: What Do We Really Know? Bahnson and Grant
    • Pitfalls in Imaging for Renal Artery Stenosis. Textor
    • § The U.S. Physician Workforce: Serious Questions Raised, Answers Needed. Garber and Sox
    • Bringing Professionalism to the Bedside. Laine and So
    • Professionalism and the Medical Student. Francis
    • ON BEING A DOCTOR: A Lesson from the Third Year. Helm
November 3                    
  1. Editorials: COX-2–specific inhibitor or proton pump inhibitor plus traditional NSAID: Is either approach sufficient for patients at highest risk of NSAID-induced ulcers? Gastroenterology. 2004;127:1256-1262.
  2. Sleepiness, Sleep-disordered Breathing, and Accident Risk Factors in Commercial Vehicle Drivers. Am. J. Respir. Crit. Care Med. 2004; 170: 1014-1021.
  3. Editorial: Sleepiness, Sleep Apnea, and Driving: Still Miles To Go Before We Safely Sleep. Am. J. Respir. Crit. Care Med. 2004; 170: 927-928.
  4. Critical Care Use during the Course of Serious Illness. Am. J. Respir. Crit. Care Med. 2004; 170: 981-986.
  5. BMJ 30 October 2004 (Vol 329, No 7473)
November 2                    
  1. Estimated phytochemical content of the Dietary Approaches to Stop Hypertension (DASH) diet is higher than in the control study diet. J Am Dietetic Assc 2004: 104 Nov [Eurekalert report]
  2. Interactions Between Hyperglycemia and Hypoxia: Implications for Diabetic Retinopathy. Diabetes 2004 53: 2931-2938 [Diabetic damage to eyes, heart, nerves, kidneys may be explained by controversial theory. Eurekalert ]
  3. IDSA Recommends Ways to Strengthen HHS's Pandemic Influenza Plan.
  4. New England Journal of Medciine Volume 351 October 28, 2004  Number 18
November 1                    
  1. JAMA. Vol. 292 No. 16, pp. 1925-E5, October 27, 2004
  2. The Lancet  Volume 364, Number 9445     30 October 2004
  3. Interrelations Between Brachial Endothelial Function and Carotid Intima-Media Thickness in Young Adults. The Cardiovascular Risk in Young Finns Study. Circulation 2004: published online before print October 25, 2004. [Medscape review]