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Recent reports in Science and Medicine for February 2005

Some of these links are very transient and may expire within days of posting. Some may require prior registration. Check-in and view frequently to avoid missing great news items. I welcome any suggested articles. (email link). "§" indicates a recommended article.

 February 28  
  1. Family-based case-control study of cigarette smoking and Parkinson disease. Neurology 2005 64: 442-447. [Eurekalert: Physical activity linked to protection from Parkinson's disease]
  2. §  Early and late mortality after myocardial infarction in men and women: prospective observational study. Heart 2005; 91: 305-307.[Medscape: Lower MI Survival in Women May Be Due to Poorer Management]
  3. Race-ethnicity–specific waist circumference cutoffs for identifying cardiovascular disease risk factors. Am J Clin Nutr 2005 81: 409-415.[Medscape: Waist Circumference Better Than BMI at Predicting Cardiac Risk]
  4. §  Cardiovascular risk factors and migraine: The GEM population-based study. Neurology 2005 64: 614-620.
  5. Maintenance of Long-Term Clinical Benefit With Sirolimus-Eluting Coronary Stents. Three-Year Results of the RAVEL Trial.Circulation 2005: published online [Abstract] [Medscape]
  6. §  Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial.BMJ, published online firest [Abstract] [Medscape]
  7. JAMA Vol. 293 No. 8, pp. 899-1024, February 23, 2005
    • §  Effects of Estrogen With and Without Progestin on Urinary Incontinence. JAMA. 2005;293:935-948.
    • §  Amoxicillin-Clavulanate vs Ciprofloxacin for the Treatment of Uncomplicated Cystitis in Women: A Randomized Trial. JAMA. 2005;293:949-955. [Medscape review]
    • §  Screening for Bipolar Disorder in a Primary Care Practice. JAMA. 2005;293:956-963. [Medscape]
    • §  Prevalence of BRCA1 and BRCA2 Mutations in Women Diagnosed With Ductal Carcinoma In Situ. JAMA. 2005;293:964-969.
    • Evaluation of New Treatments in Radiation Oncology: Are They Better Than Standard Treatments? JAMA. 2005;293:970-978.
    • Pharmacological Facilitation of Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction: Is the Slope of the Curve the Shape of the Future? JAMA. 2005;293:979-986.
    • The Rational Clinical Examination Does This Patient Have Influenza? JAMA. 2005;293:987-997.
    • Editorials Estrogen Treatment for Urinary Incontinence: Never, Now, or in the Future? JAMA. 2005;293:998-1001.
    • http://www.medscape.com/viewarticle/500014 The Case for Randomized Trials in Cancer Treatment: New Is Not Always Better. JAMA. 2005;293:1001-1003.
    • Author in the Room: A Teleconference Series to Accelerate Health Care Improvement. JAMA. 2005;293:1004.
February 25  

Weekend Reading - Basic Science and general interest articles

  1. FDA News:
  2. § Avian Flu World's No. 1 Threat, CDC Report and Medscape report
  3. Gene therapy is first deafness 'cure' [New Scientist review from Nature Medicine (DOI: 10.1038/nm1193)]
  4. Cell- and Ligand-specific Regulation of Promoters Containing Activator Protein-1 and Sp1 Sites by Estrogen Receptors alpha and beta. J. Biol. Chem. 2005 280: 347-354. [Eurekalert: Research focusing on why estrogenic hormones produce differing results]
  5. Young Blood Heals the Elderly [Science now report from 17 February Nature. ]
  6. Protein that promotes survival of stem cells might be key to poor leukemia prognosis [Eurekalert report from the February 18 issue of Science.]
 February 24  
  1. §  Use of Antimicrobial Prophylaxis for Major Surgery: Baseline Results From the National Surgical Infection Prevention Project. Arch Surg. 2005;140:174-182. [Eurekalert:
    Antimicrobials to prevent infection in major surgery are used properly only about half the time]
  2. Fasting Glucose Is an Important Independent Risk Factor for 30-Day Mortality in Patients With Acute Myocardial Infarction: A Prospective Study. Circulation 2005 111: 754 - 760.
  3. Annals of Internal Medicine February 2005  Vol. 142, Num. 4
  4. BMJ  19 February 2005  Vol. 330, No. 7488
 February 23  
  1. §  Use of Antimicrobial Prophylaxis for Major Surgery: Baseline Results From the National Surgical Infection Prevention Project. Arch Surg. 2005;140:174-182. [Eurekalert:
    Antimicrobials to prevent infection in major surgery are used properly only about half the time]
  2. Fasting Glucose Is an Important Independent Risk Factor for 30-Day Mortality in Patients With Acute Myocardial Infarction: A Prospective Study. Circulation 2005 111: 754 - 760.
  3. Annals of Internal Medicine February 2005  Vol. 142, Num. 4
  4. BMJ  19 February 2005  Vol. 330, No. 7488
 February 22                  
  1. New England Journal of Medicine   Volume 352   Number 7   February 17, 2005
  2. The Lancet Issue 9460, 19 February 2005
    • Editorial: Losing tolerance with zero tolerance
    • Editorial: Chlamydia--a testing issue
    • Effect of a p210 multipeptide vaccine associated with imatinib or interferon in patients with chronic myeloid leukaemia and persistent residual disease: a multicentre observational trial  [Summary]
    • Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial  [Summary] 
    • § Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer  [Summary]
    • Long-term survival after colorectal surgery associated with buffy-coat-poor and leucocyte-depleted blood transfusion: a follow-up study  [Summary] 
    • § Blockade of HERG channels by HIV protease inhibitors  [Full Text] 
    • Seminar: Cutaneous melanoma
    • Review: The influence of violent media on children and adolescents: a public-health approach.
    • Series: The Millennium Project: the positive health implications of improved environmental sustainability
    • Clinical Trials: A proposed charter for clinical trial data monitoring committees: helping them to do their job well .
 February 21                  
  1. JAMA Vol. 293 No. 7, pp. 771-E4, February 16, 2005 Medical Applications of Biotechnology
  2. Cardiovascular Disease in Women
  3. §  fMRI reveals large-scale network activation in minimally conscious patients. Neurology 2005 64: 514-523. [Science Daily Extensive Brain Activity During Listening To Speech Found In Minimally Conscious Patients]
  4. ACE inhibitors and protection against pneumonia in elderly patients with stroke. Neurology 2005 64: 573-574. [Medscape] (Access via PHD Library
February 18                    

Weekend Reading - Basic Science and general interest articles

  1. §  FDA - Improvements in Drug Safety Monitorings. FDA to Create Independent Drug Safety Board [News report from Washington Post]
  2. §  News reports for FDA Advisory Panel on Safety of COX-2 Inhibitors (some site require registration) {Dr.s Feldman and Cush are in attendance}
    • FDA Panel Members: All Arthritis Drugs Suspect [WebMD]
    • FDA Panel Mulls Whether All COX-2 Drugs Have Same Risk [Washington Post ]
    • Vioxx Alternative Potentially as Risky, Official Says. [Washington Post]
    • Medical Panel Poses Pointed Questions to Drug Makers Over Risks of Painkillers [NYTimes]
    • Merck May Resume Sales of Painkiller, Official Says [NYTimes]
    • FDA Scientist Questions Need for COX-2 Drugs [Medscape]
  3. FDA NEWS
    • FDA Generic and Labeling Approvals: [Medscape]
      • Generic 0.025 and 0.075 mg/day Estradiol Transdermal Systems (Climara) for Menopausal Symptoms, Other Indications
      • Generic Fentanyl Transdermal Systems 25, 50, 75, and 100 µg/hour (Duragesic) for Chronic Pain
      • Generic 750 mg Levofloxacin (Levaquin) for Bacterial Infections in Adults
      • Fenoldopam Mesylate Injection, Sabex 2002, Approval
      • Toprol XL (metoprolol succinate) Extended Release Tablets, AstraZeneca LP, New Dosage Regimen
    • FDA Approvals [Medscape review and FDA listing]
      • Vanos (Fluocinonide 0.1% Cream) for the topical treatment of plaque-type psoriasis affecting up to 10% body surface area (BSA). Fluocinonide is a class 1 corticosteroid.
      • Proxinium (Orphan Drug VB4-845) for the treatment of advanced, recurrent head and neck cancer. Proxinium is made up of a humanized single-chain antibody fragment recombinantly fused with a protein cytotoxic agent. The antibody fragment binds to an epithelial cell surface antigen found on the surface of most head and neck tumor cells, allowing its internalization and delivery of the cytotoxic component.
      • INO-1001 (Orphan Drug) to prevent postoperative complications of aortic aneurysm repair. INO-1001 is an inhibitor of poly (ADP-ribose) polymerase (PARP), a nuclear enzyme that normally recruits DNA repair enzymes to repair single-strand DNA breaks caused by oxidative stress. In situations of excessive DNA damage (such as acute exposure to a large pathological insult), overactivation of PARP results in cell-based energetic failure leading to cellular necrosis, tissue injury, and organ damage/failur
      • Follistim AQ Cartridge (follitropin beta injection), Organon, Inc., Control Supplement
 February 17                  
  1. Archives of Internal Medicine Vol. 165 No. 3, pp. 249-356, February 14, 2005
  2. §  Influence of glycemic load on HDL cholesterol in youth. Am J Clin Nutr 2005 81: 376-379.
  3. §  Direct comparison of a dietary portfolio of cholesterol-lowering foods with a statin in hypercholesterolemic participants. Am J Clin Nutr 2005 81: 380-387.
  4. The Lancet  Volume 365, Number 9459     12 February 2005
    • §  Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis--the IC study: a randomised controlled trial. IC Study Group
    • §  Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. ESAC Project Group.
    • Aseptic peritonitis due to peptidoglycan contamination of pharmacopoeia standard dialysis solution  [Summary] 
    • Parkinson's disease in China: prevalence in Beijing, Xian, and Shanghai  [Full Text] 
    • Seminar: Age-related cataract  
    • Rapid Review: Endothelial inflammation in insulin resistance
    •  SeriesMillennium Project: Emerging consensus in HIV/AIDS, malaria, tuberculosis, and access to essential medicines
    • Public Health: New strategy against Aedes aegypti in Vietnam
 February 16                  
  1. New Engalnd Journal of Medicine   February 15, 2005 Early Release
    • Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention [abstract]
    • Complications of the COX-2 Inhibitors Parecoxib and Valdecoxib after Cardiac Surgery [abstract]
    • Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial [abstract]
    • EDITORIAL:  COX-2 Inhibitors — A Lesson in Unexpected Problems
    • EDITORIAL:  COX-2 Inhibitors — Lessons in Drug Safety
  2. BMJ   12 February 2005 (Vol 330, No 7487)
    • §  Online publicaiton:: 11 February 2005 Acute treatment of moderate to severe depression with hypericum extract WS 5570 (St John's wort): randomised controlled double blind non-inferiority trial versus paroxetine. BMJ, doi:10.1136/bmj.38356.655266.82 [New Scientist review]
    • Effectiveness of speed cameras in preventing road traffic collisions and related casualties: systematic review. BMJ  2005;330:331-334.
    • Rectal artemether versus intravenous quinine for the treatment of cerebral malaria in children in Uganda: randomised clinical trial. BMJ  2005;330:334.
    • Randomised controlled trial of conservative management of postnatal urinary and faecal incontinence: six year follow up. BMJ  2005;330:337.
    • Long term psychological outcome for women with congenital adrenal hyperplasia: cross sectional survey. BMJ  2005;330:340-341.
    • Commentary: A support group's perspective. BMJ  2005;330:341
    • Monitoring changes in hospital standardised mortality ratios. BMJ  2005;330:329.
    • Primary care: Association between hormone replacement therapy and subsequent stroke: a meta-analysis. BMJ  2005;330:342
    • Commentary: Time to review all the evidence for hormone replacement therapy. BMJ  2005;330:345.
    • 10-minute consultation: Headache. BMJ  2005;330:346.
    • Clinical review: Zinc deficiency: what are the most appropriate interventions? BMJ  2005;330:347-349.
    • Lesson of the week: Azathioprine-induced pancytopenia in a patient with pompholyx and deficiency of erythrocyte thiopurine methyltransferase. BMJ  2005;330:350-351.
    • Commentary: Testing patients to allow tailored drug treatment . BMJ  2005;330:352
    • ABC of adolescence: Consent, competence, and confidentiality. BMJ  2005;330:353-356
 February 15                  
  1. §  Carotid Plaque Pathology: Thrombosis, Ulceration, and Stroke Pathogenesis. Stroke 2005 36: 253 - 257.
  2. Devices, Drugs, and the Food and Drug Administration: Increasing Implications for Ischemic Stroke. Stroke 2005 36: 398 - 399;
  3. JAMA Feb 9, 2005 Vol. 293, Num. 6
  4. BMJ 5 February 2005 (Vol 330, No 7486)
 February 14                  
  1. §  Just Get Out the Door! Importance of Walking Outside the Home for Maintaining Mobility: Findings from the Women's Health and Aging Study. E. M. Simonsick. J Am Geriatr Soc. 2005; 52: 198-203.
  2. §  Thiazolidinediones, Metformin, and Outcomes in Older Patients With Diabetes and Heart Failure: An Observational Study. Circulation 2005 111: 583 - 590
  3. Periodontal Microbiota and Carotid Intima-Media Thickness: The Oral Infections and Vascular Disease Epidemiology Study (INVEST). Circulation 2005 111: 576 - 582.
  4. New England Journal of Medicine Volume 352  February 10, 2005  Number 6
  5. American Journal of Medicine February 2005 (Vol. 118, Issue 2)  (Full-text availability on request)
    • Editorial: Doctors and the drug industry: How can we handle potential conflicts of interest? pages 99-100
    • Review: Atrial flutter and the risk of thromboembolism: A systematic review and meta-analysis. pages 101-107
    • Primary angioplasty in acute myocardial infarction: Hypothetical estimate of superiority over aspirin or untreated controls. pages 113-122 Editorial: The benefit of an invasive approach in thrombolysis-ineligible patients with acute myocardial infarction . pages 123-125
    • Cardiovascular abnormalities in hyperthyroidism: A prospective Doppler echocardiographic study. pages 126-131
    • Triiodothyronine levels for risk stratification of patients with chronic heart failure. pages 132-136
    • §  Initiation of warfarin therapy in elderly medical inpatients: A safe and accurate regimen. pages 137-142 Editorial: Tailoring warfarin induction doses to reflect individual and disease-specific factors. pages 143-144
    • Arterial carbon dioxide tension on admission as a marker of in-hospital mortality in community-acquired pneumonia. pages 145-150
    • Screening for cervical cancer: Will women accept less? pages 151-158
    • Editorial: Papanicolaou testing: When does more become less? pages 159-160
    • Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. pages 161-167
    • Consumer health information on the Internet about carpal tunnel syndrome: Indicators of accuracy . pages 168-174
    • Assessment of medical school institutional review board policies regarding compensation of subjects for research-related injury. pages 175-180
February 11                    

Weekend Reading - Basic Science and general interest articles

  1. FDA News:
    • Generic Approvals: Cleocin, Celexa, Wellbutrin SR, Monopril HCT [Medscape]
    • Zyprexa and Zyrtec Substitution Errors May Lead to Adverse Events. (Relapse of schizophrenia or bipolar disordermedication) [Medscape]
    • Fortovase (saquinavir soft gelatin capsules) Invirase (saquinavir mesylate capsules and tablets) Drug interaction warning. Drug-induced hepatitis with marked transaminase elevations has been observed in healthy volunteers receiving rifampin 600 mg once daily in combination with ritonavir 100 mg/saquinavir 1000 mg twice daily (ritonavir boosted saquinavir).[Medscape]
    • Agrylin (anagrelide hydrochloride) Change in labeling. Pharmacokinetic studies have revealed an 8-fold increase in total exposure (AUC) to anagrelide hydrochloride in patients with moderate hepatic impairment. Use of anagrelide hydrochloride has not been studied in patients with severe hepatic impairment. Labeling changes include the contraindication to the use of Agrylin in patients with severe hepatic impairment. The WARNINGS section describes the need for dosage reduction in patients with moderate hepatic impairment and the necessity of monitoring these patients carefully for cardiovascular effects.
    • Adderall XR (amphetamine) Health Canada, the Canadian drug regulatory agency, has suspended the sale of Adderall XR in the Canadian market based on U.S. post-marketing reports of sudden deaths in pediatric patients.
  2. §  Thiazide-Like Diuretics Attenuate Agonist-Induced Vasoconstriction by Calcium Desensitization Linked to Rho Kinase. Hypertension. 2005;45:233.
  3. Angiotensin II and the Endothelium: Diverse Signals and Effects. Hypertension. 2005;45:163.
  4. §  Integrating Bench With Bedside: The Role of Vaccine Therapy in the Treatment of Solid Tumors. JCO Feb 1 2005: 659–661.
  5. Most of the variation in the spread of bacterial pathogens occurs simply by chance [Science Daily report from PNAS]
  6. Physicians recommend screening for toxoplasmosis for all pregnant women, newborns. [Eurekalert report from: Risk factors for Toxoplasma gondii infection in mothers of infants with congenital toxoplasmosis: Implications for prenatal management and screening. Am J Obst Gyn 2005; 192: 564-571 on-line via Science Direct]
  7. Brief Communication: Protective effect of DNA vaccine during chemotherapy on reactivation and reinfection of Mycobacterium tuberculosis. Gene Therapy advance online publication 3 February 2005; doi:10.1038/sj.gt.3302465. [Science now: New Tuberculosis Strategy Shows Promise]
  8. J Neurosurgery: Spine Feb [Science Daily : New Way To Diagnose Sciatica May Point To A Different Cause]
 February 10                  
  1. Risk Factors for Potentially Harmful Informal Caregiver Behavior. S. R. Beach, and others. J Am Geriatr Soc 2005; 53: 255 - 261. [Eurekalert]
  2. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 2005 64: 514-523.[Medscape: Brain Language Processing Networks Maintained in Minimally Conscious State]
  3. Reduction in Albuminuria Translates to Reduction in Cardiovascular Events in Hypertensive Patients: Losartan Intervention for Endpoint Reduction in Hypertension Study. Hypertension  2005; 45:198.
  4. Stroke: Volume 36, Issue 2; February, 2005  :: Advances in Stroke 2004
  5. Changes in Body Fat and Weight After a Breast Cancer Diagnosis: Influence of Demographic, Prognostic, and Lifestyle Factors. JCO Feb 1 2005: 774–782.
  6. New England Journal of Medicine Volume 352  February 3, 2005  Number 5
  7. The Lancet  Volume 365, Number 9458     05 February 2005
    • Early online publication: Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. CoolCap Study Group
    • The whole truth and nothing but the truth? The research that Philip Morris did not want you to see  [Summary]
    • Risk of oral infection with bovine spongiform encephalopathy agent in primates  [Summary]
    • Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka  [Summary] 
    • §  Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. David J Graham, and Others.
    • Selective serotonin reuptake inhibitors in pregnant women and neonatal withdrawal syndrome: a database analysis  [Summary] 
    • Prediction of cancer outcome with microarrays: a multiple random validation strategy  [Summary] 
    • Educational inequalities in cause-specific mortality in middle-aged and older men and women in eight western European populations  [Summary]
    • Early supported discharge services for stroke patients: a meta-analysis of individual patients' data  [Summary]
    • Seminar: Mitral valve prolapse.
    • Review: Alcohol and public health.
    • Series - Millennium Project: Taking action to improve women's health through gender equality and women's empowerment
    • Public Health: The p53 tumour suppressor gene and the tobacco industry: research, debate, and conflict of interest.
 February 9                  
  1. Health Affairs Jan/Feb 2005 :: PUTTING EVIDENCE INTO PRACTICE: [via Medscape]
    1. Evidence-Based Medicine: A Unified Approach. D. M. Eddy
    2. Evidence Based? Caveat Emptor! E. P. Steinberg & B. R. Luce
    3. Quality Improvement: State Of The Science. K. G. Shojania & J. M. Grimshaw
    4. §  Global Evidence, Local Decisions. C. M. Clancy & K Cronin
    5. §  Illness And Injury As Contributors To Bankruptcy. D. U. Himmelstein [Abstract] [Eurekalert review: Illness and medical bills cause half of all bankruptcies:: 2 Million Americans financially ruined each year] [Audio report from NPR]
  2. Lymph Node Evaluation in Colorectal Cancer Patients: A Population-Based Study. J Natl Cancer Inst 2005; 97: 219-225.[Medscape]
  3. JAMA  Vol. 293 No. 5, pp. 523-644, February 2, 2005
    1. Patterns of Care for Adults With Newly Diagnosed Malignant Glioma. Glioma Outcomes Project Investigators. JAMA. 2005;293:557-564.
    2. §  Missing Clinical Information During Primary Care Visits. JAMA. 2005;293:565-571. [Medscape]
    3. §  Risk Stratification for In-Hospital Mortality in Acutely Decompensated Heart Failure: Classification and Regression Tree Analysis. ADHERE Scientific Advisory Committee, Study Group, and Investigators. JAMA. 2005;293:572-580.
    4. Longitudinal Development of Mucoid Pseudomonas aeruginosa Infection and Lung Disease Progression in Children With Cystic Fibrosis. JAMA. 2005;293:581-588.
    5. Continuous Positive Airway Pressure for Treatment of Postoperative Hypoxemia: A Randomized Controlled Trial. Piedmont Intensive Care Units Network. JAMA. 2005;293:589-595.
    6. Clinical Review: Pharmacological Treatment of Neuropsychiatric Symptoms of Dementia: A Review of the Evidence. JAMA. 2005;293:596-608.
    7. Editorials: Malignant Gliomas in 2005: Where to GO From Here? JAMA. 2005;293:615-617.
    8. §  Missing Clinical Information: The System Is Down. JAMA. 2005;293:617-619.
    9. Controversies: Improving Informed Consent and Enhancing Recruitment for Research by Understanding Economic Behavior. JAMA. 2005;293:609-612.
    10. Research Compensation and the Monetarization of Medicine. JAMA. 2005;293:613-614.
 February 8                  
  1. Clinical Gastroenterology and Hepatology online publication
    • Randomized trial of etidronate plus calcium and vitamin D for treatment of low bone mineral density in Crohn's disease. J. S. Siffledeen, and others.[Medscape]
    • Bone mineral density in relation to efficacy and side effects of budesonide and prednisolone in Crohn's disease. E. J. Schoon, and others.
    • Limiting fracture risk in Crohn's disease: Is there anything better than calcium and vitamin D? C.N. Bernstein (no online access)
  2. Prevalence and Risk Factors for Homelessness and Utilization of Mental Health Services Among 10,340 Patients With Serious Mental Illness in a Large Public Mental Health System. Am J Psychiatry 2005 162: 370-376.[Medscape]
  3. Hydrocortisone Infusion for Severe Community-acquired Pneumonia: A Preliminary Randomized Study. Am. J. Respir. Crit. Care Med. 2005; 171: 242-248.
  4. Sildenafil Inhibits Altitude-induced Hypoxemia and Pulmonary Hypertension. Am. J. Respir. Crit. Care Med. 2005; 171: 275-281.
  5. Prospective Surveillance for Pseudomonas aeruginosa Cross-Infection at a Cystic Fibrosis Center. Am. J. Respir. Crit. Care Med. 2005; 171: 257-260.
  6. Annals of Internal Medicine February 2005 Vol. 142, Num. 3
    • §  Early Release Articles: The Risk for Myocardial Infarction with Cyclooxygenase-2 Inhibitors: A Population Study of Elderly Adults. Lévesque, and others [Eurekalert]
    • §  Patients Exposed to Rofecoxib and Celecoxib Have Different Odds of Nonfatal Myocardial Infarction . Kimmel, and others [Medscape]
    • §  Outpatient Care Compared with Hospitalization for Community-Acquired Pneumonia: A Randomized Trial in Low-Risk Patients. Carratalà, and others.[Medscape]
    • Association between Screening for Osteoporosis and the Incidence of Hip Fracture. Kern, and others.
    • Responding to the Rofecoxib Withdrawal Crisis: A New Model for Notifying Patients at Risk and Their Health Care Providers. Jain, and others.
    • REVIEWS: Obstructive Sleep Apnea
    • §  CLINICAL GUIDELINES: Screening for Abdominal Aortic Aneurysm: Recommendation Statement U.S. Preventive Services Task Force
    • §  Screening for Abdominal Aortic Aneurysm: A Best-Evidence Systematic Review for the U.S. Preventive Services Task Forc
    • EDITORIALS: Cardiovascular Risks of Cyclooxygenase-2 Inhibitors: Where We Stand Now
    • Decisions about Treating Community-Acquired Pneumonia. Mandell
    • Bone Density Screening: A New Level of Evidence? Cummings
    • Using Information Technology To Transfer Knowledge: A Medical Institution Steps Up to the Plate. Badgett and Mulrow
    • ON BEING A DOCTOR: House Call
    • The Iridescence of Old Ladies. McClenahan
    • AD LIBITUM Rheumatic Feinfeld
 February 7                  
Cardiovascular Disease in Women
NHLBI-NHI_Heart_Disease_Women
   

Circulation Volume 111, Issue 4; February 1, 2005: Cardiovascular Disease in Women

American_Heart_Association
 February 2                  
  1. Recent Advances in Non-Hodgkin's Lymphoma  CME [Medscape]
  2. BMJ 29 January 2005 (Vol 330, No 7485)
    • 30 years' follow up of randomised studies of adjuvant CMF in operable breast cancer: cohort study. BMJ  2005;330:217,
    • Breast cancer mortality in Copenhagen after introduction of mammography screening: cohort study. BMJ  2005;330:220.
    • Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. BMJ  2005;330:223
    • A multiagency protocol for responding to sudden unexpected death in infancy: descriptive study. BMJ  2005;330:227-228
    • Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control study. BMJ  2005;330:230
    • Chaperones for intimate examinations: cross sectional survey of attitudes and practices of general practitioners. BMJ  2005;330:234-235.
    • 10-minute consultation: Tinnitus . BMJ  2005;330:237
    • Recent developments in atrial fibrillation . BMJ  2005;330:238-243
    • ABC of sports and exercise medicine: Female athlete triad. BMJ  2005;330:244-246,
    • Online First::: §  The nature of medical evidence and its inherent uncertainty for the clinical consultation: qualitative study. BMJ, doi:10.1136
    • §  Identifying outcome reporting bias in randomised trials on PubMed: review of publications and survey of authors. BMJ, doi:10.1136/
    • Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study. BMJ, doi:10.113
  3. Lancet Volume 365, Number 9457  29 January 2005
    • Early online publication 
      • §  Articles: Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial  [Summary]
      • Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study  [Summary]
      • The whole truth and nothing but the truth? The research that Philip Morris did not want you to see  [Summary] 
    •  Research letters: Risk of oral infection with bovine spongiform encephalopathy agent in primates  [Summary] 
    • Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial  [Summary] for the STICH investigators
    • Safety and immunogenicity of new cell-cultured smallpox vaccine compared with calf-lymph derived vaccine: a blind, single-centre, randomised controlled trial  [Summary] 
    • Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease  [Summary]  Study Group-PROGENI investigators*
    • A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease  [Summary] 
    • A common LRRK2 mutation in idiopathic Parkinson's disease  [Summary] 
    • Acute renal failure  [Summary]
    • Rapid Review: Dispelling myths in the treatment of hepatic encephalopathy  [Summary] 
    • Treating Individuals 5: Treatment with drugs to lower blood pressure and blood cholesterol based on an individual's absolute cardiovascular risk  [Full Text]
 February 1                  
  1. The association of body mass index and prostate-specific antigen in a population-based study. Cancer Early View online: 24 Jan 2005 [Medscape]
  2. Calcium from Diet and Supplements is Associated With Reduced Risk of Colorectal Cancer in a Prospective Cohort of Women. Cancer Epidemiol Biomarkers Prev 2005 14: 126-132. [Eurekalert]
  3. Poor Pregnancy Outcome in Women With Type 2 Diabetes. Diabetes Care 2005;28:323-328. [Medscape]
  4. Archives of Internal Medicine  Vol. 165 No. 2, pp. 131-244, January 24, 2005

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