News pages
2004  
June
July
August
September
October
November
December
2005    
January
February
March
April
May
June

Recent reports in Science and Medicine for September 2004

Some of these links are very transient and may expire within days of posting. Some may require prior registration. Check-in and view frequently to avoid missing great news items. I welcome any suggested articles. (email link). "§" indicates a recommended article.

September 30

  1. § FDA Issues Public Health Advisory on Vioxx as its Manufacturer Voluntarily Withdraws the Product
  2. Tuberculosis Transmission at Renal Dialysis Center [Medscape report from MMWR]
  3. BMJ 25 September 2004 (Vol 329, No 7468)
  4. Lancet Volume 364, Number 9440     25 September 2004

September 29

  1. § Decreased brain dopaminergic transporters in HIV-associated dementia patients. Brain online Aug 19, 2004 [ScienceDaily news report]
  2. The Effect of Tumor Size on Curability of Stage I Non-small Cell Lung Cancers.Chest 2004 126: 761-765.
  3. Dieting and the development of eating disorders in obese women: results of a randomized controlled trial. Am J Clin Nutr 2004 80: 560-568. [Medscape]
  4. § Obesity Is an Independent Risk Factor of Mortality in Severely Injured Blunt Trauma Patients. Arch Surg. 2004;139:983-987.
  5. Antidepressants: An Avoidable and Solvable Controversy. Ann Pharmacotherapy: 2004;38,:1743-1746. [Eurekalert]
  6. § Essential Amino Acid and Carbohydrate Supplementation Ameliorates Muscle Protein Loss in Humans during 28 Days Bedrest. J Clin Endocrinol Metab 2004 89: 4351-4358. [Medscape review]
  7. Antidepressants, Suicide, and the FDA: A Loose Association. Ann Pharmacotherapy: 2004. 38 :1739-1742.
  8. The Burden of Adult Hypertension in the United States 1999 to 2000: A Rising Tide. Hypertension 2004 44: 398-404. [Editorial: Hypertension in the 21st Century: The Tide Is Rising; Our Daze Must End. Hypertension 2004 44: 389.]
  9. Inhibition of Cyclooxygenase-2 in the Rat Renal Medulla Leads to Sodium-Sensitive Hypertension. Hypertension 2004 44: 424-428
  10. New England Journal of Medicine Volume 351 September 23, 2004 Number 13

September 28

  1. § Decreased brain dopaminergic transporters in HIV-associated dementia patients. Brain online Aug 19, 2004 [ScienceDaily news report]
  2. The Effect of Tumor Size on Curability of Stage I Non-small Cell Lung Cancers.Chest 2004 126: 761-765.
  3. Dieting and the development of eating disorders in obese women: results of a randomized controlled trial. Am J Clin Nutr 2004 80: 560-568. [Medscape]
  4. § Obesity Is an Independent Risk Factor of Mortality in Severely Injured Blunt Trauma Patients. Arch Surg. 2004;139:983-987.
  5. Antidepressants: An Avoidable and Solvable Controversy. Ann Pharmacotherapy: 2004;38,:1743-1746. [Eurekalert]
  6. § Essential Amino Acid and Carbohydrate Supplementation Ameliorates Muscle Protein Loss in Humans during 28 Days Bedrest. J Clin Endocrinol Metab 2004 89: 4351-4358. [Medscape review]
  7. Antidepressants, Suicide, and the FDA: A Loose Association. Ann Pharmacotherapy: 2004. 38 :1739-1742.
  8. New England Journal of Medicine Volume 351 September 23, 2004 Number 13
  9. The Burden of Adult Hypertension in the United States 1999 to 2000: A Rising Tide. Hypertension 2004 44: 398-404. [Editorial: Hypertension in the 21st Century: The Tide Is Rising; Our Daze Must End. Hypertension 2004 44: 389.]
  10. Inhibition of Cyclooxygenase-2 in the Rat Renal Medulla Leads to Sodium-Sensitive Hypertension. Hypertension 2004 44: 424-428

September 27

  1. Insights Into Causal Pathways for Ischemic Heart Disease. Adverse Childhood Experiences Study. Circulation: online September 20, 2004, CIR.0000143074. 54995.7F
  2. Predictors of Heart Failure Among Women With Coronary Disease. Circulation 2004 110: 1424 - 1430.
  3. Estrogen Modulates Inflammatory Mediator Expression and Neutrophil Chemotaxis in Injured Arteries. Circulation. 2004;110:1664-1669.
  4. § Markers of Inflammation and Rapid Coronary Artery Disease Progression in Patients With Stable Angina Pectoris. Circulation online September 20, 2004, CIR.0000142664. 18739.92.
  5. Long-Term Mortality of Patients With Acute Myocardial Infarction in the United States and Canada. Comparison of Patients Enrolled in Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I . Circulation online September 20, 2004, .CIR.0000142671. 06167.91.[Medscape review:
    Reluctance to Revascularize Reduces Long-Term Survival After MI]
  6. Terms and Conditions: Semantic Complexity and Aspirin Resistance. Circulation 2004 110: 1706 - 1708
  7. Impact of the Bienestar School-Based Diabetes Mellitus Prevention Program on Fasting Capillary Glucose Levels: A Randomized Controlled Trial. Arch Pediatr Adolesc Med. 2004;158:911-917.
  8. § Nesiritide Does Not Improve Renal Function in Patients With Chronic Heart Failure and Worsening Serum Creatinine. Circulation 2004 110: 1620 - 1625.
  9. Single-Arm Study of Bridging Therapy With Low-Molecular-Weight Heparin for Patients at Risk of Arterial Embolism Who Require Temporary Interruption of Warf+arin. Circulation. 2004;110:1658-1663.
  10. § Circulating Mononuclear Cells in the Obese Are in a Proinflammatory State. Circulation 2004 110: 1564 - 1571.
  11. Incidence and Predictors of Low Chemotherapy Dose-Intensity in Aggressive Non-Hodgkin's Lymphoma: A Nationwide Study. J Clin Onc 2004; online JCO.2004.03.213.
  12. JAMA Vol. 292 No. 12 September 22/29, 2004

SEPTEMBER 24

Weekend Reading - Basic Science and general interest articles

  1. § U.S. Child Health Worse Than Other Industrialized Countries. News report Johns Hopkins Bloomberg School of Public Health and September/October 2004 issue of the journal Health Affairs.
  2. Enhancing the hominoid brain. The Scientist report and Science now (Gene Made Apes Smarter) from Nature Genetics.
  3. Gastroenterology, CT colonography has significant promise. [Eurekalert]
  4. Pharmacovigilance in the 21st Century: New Systematic Tools for an Old Problem. Pharmacotherapy 2004; 24: 1099-1104.
  5. Breast Cancer Associated With Melanoma Risk, and Vice Versa. [Medscape review from Int J Cancer 2004;111:792-794.]
  6. NCQA Releases State of Health Care Quality 2004: Major Gains in Health Care Quality, But Only For 1/4 of System :: Annual toll: 42,000 - 79,000 avoidable deaths, 66.5 million sick days and $1.8 billion in excess medical costs.(pdf link)
  7. § Alcohol Tied to 75,000 Deaths a Year in U.S.[Medscape review of CDC report]
  8. § MMWR :: Notice to Readers: Supplemental Recommendations About the Timing of Influenza Vaccination, 2004--05 Season

September 23

  1. § The Evolving Paradigm of Hyperglycemia and Critical Illness. Chest. 2004;126:674-676.
  2. Bone Marrow Dosimetry and Safety of High 131I Activities Given After Recombinant Human Thyroid-Stimulating Hormone to Treat Metastatic Differentiated Thyroid Cancer. J Nucl Med 2004 45: 1549-1554. [New technique for thyroid cancer therapy eliminates many side effects. Science Daily]
  3. Annals of Internal Medicine 21 September 2004 Volume 141 Issue 6
    • § Association of Hemoglobin A1c with Cardiovascular Disease and Mortality in Adults: The European Prospective Investigation into Cancer in Norfolk. Khaw, et al.
    • § Meta-Analysis: Glycosylated Hemoglobin and Cardiovascular Disease in Diabetes Mellitus. Selvin, et al.
    • § Manipulative Therapy in Addition to Usual Medical Care for Patients with Shoulder Dysfunction and Pain: A Randomized, Controlled Trial. Bergman, et al.
    • § Comparison of Clinical Criteria for the Acute Respiratory Distress Syndrome with Autopsy Findings. Esteban, et al.
    • Improving Patient Care Improvements in 1-Year Cardiovascular Clinical Outcomes Associated with a Hospital-Based Discharge Medication Program. Lappé, et al.
    • Update in Oncology. Stein
    • The Acute Respiratory Distress Syndrome. Piantadosi and Schwartz
    • When Most Doctors Are Women: What Lies Ahead? Levinson and Lurie
    • Editorials Glycosylated Hemoglobin: Finally Ready for Prime Time as a Cardiovascular Risk Factor. Gerstein
    • Clinical Trial Registration: A Statement from the International Committee of Medical Journal Editors. De Angelis, et al.
    • On Being a Doctor Foreign Body of the Heart. Zaroff
  4. The Lancet Volume 364, Number 9439 | 18 September 2004
    • § Culture of Mycobacterium avium subspecies paratuberculosis from the blood of patients with Crohn's disease  [Summary] 
    • § Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1): a randomised controlled trial  [Summary] 
    • Tacrolimus and steroids versus ciclosporin microemulsion, steroids, and azathioprine in children undergoing liver transplantation: randomised European multicentre trial  [Summary] 
    • Suicide and the unique prevalence pattern of schizophrenia in mainland China: a retrospective observational study  [Full Text] 
    • Global health and moral values  [Summary] 
    • Health and social justice  [Full Text]
    • Rediscovering human dignity  [Full Text] 
    • Bioethics, health, and inequality  [Full Text]
    • Ethics of the social determinants of health  [Full Text] 

September 22

  1. Mayo Clinic Proceedings |September 2004  Volume 79  Number 9
    • Editorial: Peripheral Arterial Disease in the Catheterization Laboratory: An Underdetected and Undertreated Risk Factor
    • Evaluation and Epidemiological Research in Tuberculosis Control: Linking Medical Care and Public Health (link)
    • § Effect of Peripheral Arterial Disease in Patients Undergoing Percutaneous Coronary Intervention With Intracoronary Stents (link)
    • Incidence of Tuberculosis in Olmsted County, Minnesota, 1990-2001(link)
    • § Early Life Risk Factors for Attention-Deficit/Hyperactivity Disorder: A Population-Based Cohort Study [Eurekalert] (link)
    • Robot-Assisted Laparoscopic Cholecystectomy: Initial Mayo Clinic Scottsdale Experience
    • Linezolid Therapy for Orthopedic Infections
    • Motivating Factors for Academic Physicians Within Departments of Medicine
    • Pulmonary Involvement in Henoch-Schönlein Purpura
    • Primary Care Perspective on Bariatric Surgery
    • Minimally Invasive Radical Prostatectomy
    • Carotid Revascularization for Prevention of Stroke: Carotid Endarterectomy and Carotid Artery Stenting
  2. BMJ 18 September 2004 (Vol 329, No 7467)

September 21

  1. Influence of alcohol consumption on restenosis rate after percutaneous transluminal coronary angioplasty and stent implantation. Heart 2004; 90: 1189-1193.
  2. § Intravenous immunoglobulins containing antibodies against ß-amyloid for the treatment of Alzheimer’s disease. J Neurol Neurosurg Psychiatry 2004; 75: 1472-1474. [Eurekalert]
  3. The anal reflex elicited by cough and sniff: validation of a neglected clinical sign. J Neurol Neurosurg Psychiatry 2004; 75: 1449-1451.
  4. § Effect of Pravastatin on Cardiovascular Events in People With Chronic Kidney Disease. Circulation 2004: published online before print September 13, 2004, 10.116 [Medscape]
  5. Influence of dietary factors on the clinical course of ulcerative colitis: a prospective cohort study. Gut 2004; 53: 1479-1484.
  6. Many Women Get First Mammogram, Delay Further Ones SOURCE: Cancer, online edition September 13, print edition October 15, 2004.
  7. Should CA-125 Response Criteria Be Preferred to Response Evaluation Criteria in Solid Tumors (RECIST) for Prognostication During Second-Line Chemotherapy of Ovarian Carcinoma? Early Release: J Clin Oncology, 2004;10.1200/JCO.2004.10.028
  8. New England Journal of Medicine Volume 351 September 16, 2004 Number 12 Summaries
    • § Becoming a Physician: Learner-Centered Medical Education. Ludmerer
    • Becoming a Physician: Match Point? Wright and Katz
    • Doctors and Patients: Just the Facts. Campo
    • Changing the Cell Source in Cell Therapy? Pellegrini Catheter Ablation for Cardiac Arrhythmias. Wellens
    • § Talking about Death with Children Who Have Severe Malignant Disease. Kreicbergs and Others
    • § Corneal Reconstruction with Tissue-Engineered Cell Sheets Composed of Autologous Oral Mucosal Epithelium. Nishida and Others
    • Radiofrequency Ablation in Children with Asymptomatic Wolff–Parkinson–White Syndrome. Pappone and Others
    • Peginterferon Alfa-2a Alone, Lamivudine Alone, and the Two in Combination in Patients with HBeAg-Negative Chronic Hepatitis Marcellin and Others
    • Current Concepts: Cystic Neoplasms of the Pancreas. Brugge and Others
    • Medical Progress: Turner's Syndrome. Sybert and McCauley
    • § Clinical Trial Registration: A Statement from the International Committee of Medical Journal Editors. C. De Angelis and Others
    • Should Parents Speak with a Dying Child about Impending Death? L. Wolfe
    • Artificial Sweeteners — Enhancing Glycosylation to Treat Muscular Dystrophies. T. A. Rando

September 20

  1. In vitro differentiation of rat liver derived stem cells results in sensitization to TNF-mediated apoptosis. Hepatology 2004; 40:590 - 599.[Gene expression in liver tumors and patient prognosis: Eurekalert]
  2. Effects of Oral Contraceptives on Body Composition and Physical Performance in Female Athletes. J Clin Endocrinol Metab 2004 89: 4364-4370.[Medscape]
  3. Canadian Medical Association Journal September 14 2004, Volume 171, Issue 6
    • Death and renal transplantation among Aboriginal people undergoing dialysis. CMAJ 2004 171: 577-582
    • A prospective cohort study of pregnancy risk factors and birth outcomes in Aboriginal women. CMAJ 2004 171: 585-589
    • Thunderclap headache and reversible segmental cerebral vasoconstriction associated with use of oxymetazoline nasal spray. CMAJ 2004 171: 593-594
    • Tips for learners of evidence-based medicine: 2. Measures of precision (confidence intervals). CMAJ 2004 171: 611-615
  4. JAMA Vol. 292 No. 11, pp. 1269-1394, September 15, 2004

SEPTEMBER 17

Weekend Reading - Basic Science and general interest articles

  1. FDA Approves Cymbalta, Health Claim for Omega-3 Fatty Acids, in2it Hemoglobin A1c Test, and Others [Medscape report]
  2. FDA Safety Labeling Changes: Humira, Inderal LA, ProSom, and Others. [Medscape report] Adalimumab (Humira) Associated With Risk of Malignancy, Other Adverse Events | Estazolam (ProSom) Interacts With CYP-3A4 Inhibitors/Inducers | Mirtazapine (Remeron, Remeron SolTabs) May Cause Worsening of Depression, Suicidality
  3. FDA Paper: FDA Clears Over-the-Counter Sale of Automatic External Defibrillator
  4. FDA Statement on Recommendations of the Psychopharmacologic Drugs and Pediatric Advisory Committees
  5. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance J. Clin. Invest. 2004 114: 828-836. [Eurekalert: Joslin researchers clarify mechanisms for beta-cell formation]
  6. U.S. soft drink consumption grew 135% since 1977, boosting obesity .[Eurekalert and UNC news release from October issue of the American Journal of Preventive Health.
  7. Mayo Clinic researchers define link between eosinophils and asthma [Eurekalert Sept. 17, 2004, issue of Science]
  8. Synergistic interactions of lipids and myelin basic protein. PNAS 2004; 101:13466-13471. [Science Daily: Multiple Sclerosis Discovery Sheds Light On Unravelling Of Nerves' Protective Myelin Sheath]
  9. Studies Examine Dieting Practices among High School Students and if Calcium-Rich Diets Make a Difference for Girls’ Weight. J Am Dietetic Association; Sept 2004 [ADA news releaase]
  10. Why mutations in the adenomatous polyposis coli (APC) tumor suppressor gene mutant gene causes colon cancer [Eurekalert report from online early release J. Biol. Chem, 10.1074: Adenomatous polyposis coli control of retinoic acid biosynthesis is critical for zebrafish intestinal development and differentiation]

September 16

  1. Aortic Calcification and the Risk of Osteoporosis and Fractures. J Clin Endocrinol Metab 2004 89: 4246-4253. [Medscape]
  2. Onset of Frailty in Older Adults and the Protective Role of Positive Affect. Psychology and Aging, 2004, Vol. 19, No. 3, 402–408
  3. § Master’s performance in the New York City Marathon 1983–1999. Br J Sports Med 2004 38: 408-412.(Older runners improve faster)
  4. A Prospective Study of Red Meat Consumption and Type 2 Diabetes in Middle-Aged and Elderly Women: The Women’s Health Study. Diabetes Care 2004 27: 2108-2115.
  5. Breathing and mental health problems widespread among Ground Zero rescue and recovery workers. [Eurekalert report from Sept 10, 2004 MMWR]
  6. Total Dream Loss: A Distinct Neuropsychological Dysfunction after Bilateral PCA Stroke. Ann Neurol DOI: 10.1002/ana.20246. [Eurekalert report]
  7. Lancet | Volume 364, Number 9438     11 September 2004
    • How can cross-country research on health risks strengthen interventions? Lessons from INTERHEART
    • § Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study . INTERHEART Study Investigators
    • § Association of psychosocial risk factors with risk of acute myocardial infarction in 11119 cases and 13648 controls from 52 countries (the INTERHEART study): case-control study. INTERHEART investigators
    • MMR vaccination and pervasive developmental disorders: a case-control study. Smeeth, and Others.
    • Effect of a participatory intervention with women's groups on birth outcomes in Nepal: cluster-randomised controlled trial. MIRA Makwanpur trial team
    • Antenatal anthelmintic treatment, birthweight, and infant survival in rural Nepal. Christian, and Others
    • Prospects for new drugs for chronic obstructive pulmonary disease. Barnes and Hansel
    • Health care in Cuba and the manipulation of humanitarian imperatives. Garfield
    • Trauma of Chechnya's ongoing war on internally displaced people. Jong, and Others.
    • Tears from the land of snow: health and human rights in Tibet. Singh
    • Informed choices for attaining the Millennium Development Goals: towards an international cooperative agenda for health-systems research. Task Force on Health Systems Research
    • The state of primary-care research. Mant, and Others
    • Uses of Error: Being wrong in the right direction? Aaby
  8. Archives of Internal Medicine Vol. 164 No. 16, pp. 1715-1816, September 13, 2004
September 15
    1. § Effect of Aging and Physical Activity on Left Ventricular Compliance. Circulation 2004: published online CIR.0000142863.71285.74. [Eurekalert]
    2. Recombinant hepatitis B vaccine and the risk of multiple sclerosis: A prospective study. Neurology 2004 63: 838-842. [Medscape]
    3. Under use of necessary care among cancer survivors. Cancer 2004 Published Online: 13 Sep 2004. [Medscape]
    4. Improvement of motor function in early Parkinson disease by safinamide. Neurology 2004 63: 746-748. [Medscape]
    5. Drug therapy reduces risk of stroke during coronary artery bypass surgery Eurekalert Citation: Journal of Thoracic and Cardiovascular Surgery. Vol. 121, Issue 3, September 2004.
    6. New England Journal of Medicine Volume 351 September 9, 2004 Number 11
    7. BMJ 11 September 2004 (Vol 329, No 7466)

September 13

  1. § What do evidence-based secondary journals tell us about the publication of clinically important articles in primary healthcare journals? BMC Medicine 2004, 2:33.
  2. Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori. Am J Clin Nutr 2004 80: 737-741. [Medscape report]
  3. Echocardiographic Evaluation of Asymptomatic Parental and Sibling Cardiovascular Anomalies Associated With Congenital Left Ventricular Outflow Tract Lesions. Pediatrics 2004; 114: 691-696.
  4. § A Randomized Controlled Trial of an Information Prescription for Pediatric Patient Education on the Internet. Arch Pediatr Adolesc Med. 2004;158:857-862.
  5. Archives of Internal Medicine Vol. 164 No. 15, pp. 1595-1708, August 9/23, 2004

SEPTEMBER 10

  1. § Annals of Internal Medicine Early Release: Clinical Trial Registration: A Statement from the International Committee of Medical Journal Editors. International Committee of Medical Journal Editors. 21 September 2004 | Volume 141 Issue 6
  2. § Clinical Trial Registration: A Statement from the International Committee of Medical Journal Editors. Published at www.nejm.org September 8, 2004 (10.1056/NEJMe048225)
  3. § Early Release Article, posted September 8, 2004 :: A Statement From the International Committee of Medical Journal Editors. JAMA. 2004;292
  4. § Clinical trial registration: a statement from the International Committee of Medical Journal Editors Lancet   11 September 2004 ; 364, Number 9438
    Catherine De Angelis, Editor-in-Chief, JAMA Jeffrey M Drazen, Editor-in-Chief, New England Journal of Medicine Frank A Frizelle, Editor, New Zealand Medical Journal Charlotte Haug, Editor-in-Chief, Norwegian Medical Journal John Hoey, Editor, CMAJ Richard Horton, Editor, The Lancet Sheldon Kotzin, Executive Editor, MEDLINE Christine Laine, Senior Deputy Editor, Annals of Internal Medicine Ana Marusic, Editor, Croatian Medical Journal A John P M Overbeke, Executive Editor, Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine) Torben V Schroeder, Editor, Journal of the Danish Medical Association Hal C Sox, Editor, Annals of Internal Medicine Martin B Van Der Weyden, Editor, Medical Journal of Australia.
  5. [ News@Nature and New Scientist: Medical journals to require clinical trial registration ]

Weekend Reading - Basic Science and general interest articles

  1. FDA News :: FDA Approves Cymbalta (duloxetine hydrochloride) for Neuropathic Pain Associated With Diabetes
  2. Trans fatty acids: EFSA Panel reviews dietary intakes and health effects. The Scientific Panel on Dietetic Products, Nutrition and Allergies (NDA) of the European Food Safety Authority
  3. § Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche. [Eurekalert and Science now report from Cell, Vol 118, 635-648, 3 Sept 2004] (Potential "good news" for the bald)
  4. Extreme Stretch Growth of Integrated Axons. J. Neurosci. 2004 24: 7978-7983; [Eurekalert]
  5. § Netrin-1 controls colorectal tumorigenesis by regulating apoptosis. Nature 431, 80 - 84 (02 September 2004); doi:10.1038. [Mehlen and his colleagues describe a third class of cancer-controlling genes, "conditional suppressors"]
  6. Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Hum. Mol. Genet. 2004 13: 1903-1911.
  7. Researchers illuminate cause of Charcot-Marie-Tooth (CMT) disease. [Eurekalert news from Nature ]

September 9

  1. Annals of Internal Medicine: 7 September 2004 Volume 141 Issue 5
  2. BMJ 4 September 2004 (Vol 329, No 7465)
    • § Isolation measures in the hospital management of methicillin resistant Staphylococcus aureus (MRSA): systematic review of the literature. BMJ  2004;329:533
    • § Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study. BMJ  2004;329:539.
    • Women's reasons for not participating in follow up visits before starting short course antiretroviral prophylaxis for prevention of mother to child transmission of HIV: qualitative interview study. BMJ  2004;329:543.
    • Relation between online "hit counts" and subsequent citations: prospective study of research papers in the BMJ. BMJ  2004;329:546-547.
    • Effect of lactobacillus in preventing post-antibiotic vulvovaginal candidiasis: a randomised controlled trial. BMJ  2004;329:548.
    • Identification of potential candidates for varicella vaccination by history: questionnaire and seroprevalence study. BMJ  2004;329:551-552.
    • Recent developments in Bell's palsy. BMJ  2004;329:553-557
    • Lesson of the week: Rare causes of haemoptysis in suspected pulmonary embolism. BMJ ;2004;329:557-558
    • ABC of sexual health: Sexual problems associated with infertility, pregnancy, and ageing. BMJ 2004;329:559-561
    • Understanding health care in the south Caucasus: examples from Armenia. BMJ  2004;329:562-565
    • Consent to the publication of patient information. BMJ  2004;329:566-568.
  3. Trans fatty acids: EFSA Panel reviews dietary intakes and health effects. The Scientific Panel on Dietetic Products, Nutrition and Allergies (NDA) of the European Food Safety Authority [News: Europeans Eat Less of Dangerous Fats]
  4. Accidental Injuries Are 5th Leading Killer in the U.S. MMWR Sept. 3, 2004; vol 53 [Medscape and news report from WebMD]

SEPTEMBER 8

  1. § Mortality in HIV-Seropositive versus -Seronegative Persons in the Era of Highly Active Antiretroviral Therapy: Implications for When to Initiate Therapy. JID 2004; 190: 1046 .
  2. Therapy for Early HIV Infection: How Far Back Should the Pendulum Swing? JID 2004; 190: 1043  
  3. IDSA Press Release :: Should AIDS Therapy Be Used Earlier Than Current Guidelines Recommend?
  4. § Body Mass Index, Physical Activity, and the Risk of Decline in Overall Health and Physical Functioning in Late Middle Age. Am J Public Health 2004 94: 1567-1573. [Medscape review]
  5. § Early Statin Treatment in Patients With Acute Coronary Syndrome: Demonstration of the Beneficial Effect on Atherosclerotic Lesions by Serial Volumetric Intravascular Ultrasound Analysis During Half a Year After Coronary Event: The ESTABLISH Study. Circulation. 2004;110:1061-1068.
  6. § Footwear Style and Risk of Falls in Older Adults. J Am Geriatrics Soc 2004; 52: 1495.
  7. Psychological, Behavioral, and Immune Changes After a Psychological Intervention: A Clinical Trial . JCO Sep 1 2004: 3570–3580.
  8. New England Journal of Medicine | Volume 351 September 2, 2004 Number 10

September 7

  1. § Probabilities of Death From Breast Cancer and Other Causes Among Female Breast Cancer Patients. J Natl Cancer Inst 2004; 96: 1311-1321.[Eurekalert]
  2. § IDSA GUIDELINES : Primary Care Guidelines for the Management of Persons Infected with Human Immunodeficiency Virus: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America. Clinical Infectious Diseases 2004;39:609-629
  3. The Lancet Volume 364, Number 9437 | 04 September 2004
    • § Early online publication : Effect of potentially modifiable risk factor associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. INTERHEART Study Investigators
    • Association of psychosocial risk factors with risk of acute myocardial infarction in 11 119 cases and 13 648 controls from 52 countries. INTERHEART investigators
    • Editorial: Animal research is a source of human compassion, not shame.
  4. Lancet | Volume 364, Number 9436 | 31 August 2004
    • § Early online publication: Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomized controlled trial. ACTION (A Coronary disease Trial Investigating Outcome with Nifedipine gastrointestinal therapeutic system) investigators*
    • Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial. The EVAR trial participants*
    • Contemplating ACTION--long-acting nifedipine in stable angina. Psaty and Furberg
    • Resistant influenza A viruses in children treated with oseltamivir: descriptive study. Kiso, et al.
    • Growth and transplantation of a custom vascularised bone graft in a man. Warnke, et al.
    • Mortality and incidence of cancer during 10-year follow-up of the Scandinavian Simvastatin Survival Study (4S). The 4S Group*
    • § Mechanisms of Disease: Effects of dietary glycaemic index on adiposity, glucose homoeostasis, and plasma lipids in animals. Pawlak, et al.
    • A population-based nationwide study of parents' perceptions of a questionnaire on their child's death due to cancer. Kreicbergs, et al.
    • Efficacy of 10-day melarsoprol schedule 2 years after treatment for late-stage gambiense sleeping sickness. Schmid, et al.
    • Treatment of stable chronic obstructive pulmonary disease. Rennard
  5. Physical Symptoms Appear To Predict Cancer Prognosis [Science Daily report from online edition of CANCER,
  6. Temperature And Humidity Can Affect LASIK Surgery Results. [Science Daily from Journal of Cataract and Refractive Surgery.]
  7. Burden of Illness in Cancer Survivors: Findings From a Population-Based National Sample. J Natl Cancer Inst 2004; 96: 1322-1330.
  8. Traffic-related Air Pollution near Busy Roads: The East Bay Children's Respiratory Health Study. Am. J. Respir. Crit. Care Med. 2004; 170: 520-526.

September 3

Weekend Reading - Basic Science and general interest articles

  1. FDA News release: Geodon (ziprasidone) Revision to the WARNINGS -increased risk of hyperglycemia and diabetes in patients taking Geodon. FDA has asked all manufacturers of atypical antipsychotic medications to add this Warning statement to labeling.
  2. FDA Drug and Device Approvals: Zelnorm, Taxotere, Merci Retriever, and Others [Medscape report]
  3. Infliximab Associated With Risk of Hematologic, Neurologic Adverse Events [Medscape report of MedWatch alert]
  4. Plasminogen Is a Critical Host Pathogenicity Factor for Group A Streptococcal Infection. Science, Vol 305, Issue 5688, 1283-1286 [New Scientist report]
  5. Images reveal how rotavirus - leading cause of diarrhea - enters cells [Eurekalert report from study published in the August 26th edition of Nature]
  6. Imaging inflammation of the pancreatic islets in type 1 diabetes. PNAS 2004 vol. 101 | no. 34 | 12634-12639 [Eurekalert report]
  7. Docosahexaenoic Acid Protects from Dendritic Pathology in an Alzheimer's Disease Mouse Model. Neuron, Vol 43, 633-645, 2 September 2004 [Science now: How Fish Fat Fights Alzheimer's]
  8. Recreational fishers may be having a larger impact than previously thought.[Science now and New Scientist reports from Science].
  9. Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J. Clin. Invest. 2004 114: 529-541. ["Good" Cholesterol Carrier Deactivated in Heart Disease - Science news report]
  10. Carbon Monoxide's Two-Pronged Attack [Science now from PNAS]
  11. Short term memory's effectiveness influenced by sight, sound.[Eurekalert report from Nature Neuroscience ]
  12. Implantable contact lens (ICL) to correct myopia, are safe, effective and have predictable results for correcting moderate to high myopia or nearsightedness. These are the conclusions discussed in an article published in the September issue of Ophthalmology, [Eurekalert]

September 2

  1. The IPSO study: ibuprofen, paracetamol study in osteoarthritis. A randomised comparative clinical study comparing the efficacy and safety of ibuprofen and paracetamol analgesic treatment of osteoarthritis of the knee or hip. Ann Rheum Dis 2004; 63: 1028-1034.
  2. A randomized, 48-week, placebo-controlled trial of intensive lifestyle modification and/or metformin therapy in overweight women with polycystic ovary syndrome: A pilot study. Fertil Steril 2004; 82: 421-429 .
  3. Efficacy of etanercept in the treatment of acute, severe sciatica: a pilot study. Ann Rheum Dis 2004; 63: 1120-1123.
  4. § Allogeneic Lymphocytes Induce Tumor Regression of Advanced Metastatic Breast Cancer. JCO published 08-16, 2004,10.1200/JCO.2004.01.127
  5. JAMA. 2004;292:1007.

September 1

  1. § Early Release: Early Intensive vs a Delayed Conservative Simvastatin Strategy in Patients With Acute Coronary Syndromes: Phase Z of the A to Z Trial. JAMA 2004;292:;.1307.
  2. § Long-Term Outcome in Elderly Patients With Chronic Angina Managed Invasively Versus by Optimized Medical Therapy. Four-Year Follow-Up of the Randomized Trial of Invasive Versus Medical Therapy in Elderly Patients (TIME). Circulation 2004: published online Aug 30, 2004, 10.1161.
  3. Modulating Angiogenesis. The Yin and the Yang in Ginseng. Circulation 2004: published online Aug 30, 2004, 10.1161 [Eurekalert report]
  4. Synovial Fibroblasts from Patients with Rheumatoid Arthritis, Like Fibroblasts from Graves’ Disease, Express High Levels of IL-16 When Treated with Igs against Insulin-Like Growth Factor-1 Receptor. J Immunol 2004 173: 3564-3569.
  5. § Impact of the Metabolic Syndromine on Mortality From Coronary Heart Disease, Cardiovascular Disease, and All Causes in United States Adults. Circulation 2004: published online before print August 23, 2004, 10.1161
  6. Visceral Periadventitial Adipose Tissue Regulates Arterial Tone of Mesenteric Arteries. Hypertension 2004 44: 271-276,
  7. Statin Therapy After Acute Ischemic Stroke in the Heart Protection Study: Is the Role in Recurrent Stroke Prevention Now Defined? Stroke 2004 35: 2233 - 2234
  8. Estimated Radiation Risks Potentially Associated with Full-Body CT Screening. Radiology 2004 232: 735-738. [Science Daily report: Full-body CT Screening Increases Risk Of Cancer Death]
  9. CMAJ August 31 2004, Volume 171, Issue 5