Recent reports in Science and Medicine for August 2005
Some of these links are very transient and may expire within days of posting.
Some may require prior registration. Check-in and view frequently to avoid missing great news items. I welcome any suggested articles. (email
link). An "*" indicates
a recommended article.
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31 ::::::: |
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- * ADA Statement:
The Metabolic Syndrome: Time for a Critical Appraisal: Joint statement
from the American Diabetes Association and the European Association for
the Study of Diabetes. Diabetes
Care 2005 28: 2289-2304
- ADA Workgroup Report: Recommendations for Management of Diabetes During
Ramadan, Diabetes Care 2005 28: 2305-2311.
- The Role of Antigenic Drive and Tumor-Infiltrating Accessory Cells in the Pathogenesis of Helicobacter-Induced Mucosa-Associated Lymphoid Tissue Lymphoma
Am J Pathol 2005 167: 797-812. [Antibiotics May Not Be Enough To Stop
Recurrent Gastric Lymphoma: Science Daily]
| ::::::: August
30 ::::::: |
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- New
England Journal of Medicine Volume 353 August 25, 2005 Number 8
- Incomplete screening flexible sigmoidoscopy associated with female sex, age, and increased risk of colorectal cancer.
Gut 2005;54:1273-1278.
| ::::::: August
29 ::::::: |
|
- Suicide attempts in clinical trials with paroxetine randomised against placebo. BMC
Medicine 2005, 3:14 doi:10.1186/1741-7015-3-14. [Eurekalert]
- Changes in Body Weight and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers. Breast
Cancer Research 2005, 7:R833-R843. [Eurekalert]
- Statins and Prostate Cancer Risk: A Case-Control Study. Am.
J. Epidemiol. 2005 162: 318-325; doi:10.1093/aje/kwi203. [Medscape]
- Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid,
and Memory.
J. Neurosci. 2005 25: 7709-7717. [Eurekalert:
Brain activity in youth may presage Alzheimer's pathology]
- MMWR. 2005;54;793-796 [Medscape review]
| ::::::: August
26 ::::::: |
Weekend
Reading - Basic Science and general interest articles
|
|
- FDA Safety Labeling Changes: [Medscape]
- Requip (ropinirole) risk of somnolence,
and rarer risks of syncope, hypotension, and hallucinations in
patients with moderate to severe primary restless legs syndrome
(RLS).
- Lodine (etodolac) risk of serious
gastrointestinal (GI) toxicities, including inflammation, bleeding,
ulceration, and perforation of the stomach, small intestine, or
large intestine.
- Zestril (lisinopril) rare risk
of head/neck angioedema and hepatic failure associated with its
use.
- Facilitation of Task Performance and Removal of the Effects of Sleep
Deprivation by an Ampakine (CX717) in Nonhuman Primates. PLOS
Biology Volume 3 | Issue 9 | Sept 2005.[Staying Smart Without Sleep. ScienceNOW
report]
- Clocking in Pillow Time without the Pillow. PLOS
Biology DOI: 10.1371/journal.pbio.0030308 Published: August 23, 2005.
- Placebo Effects Mediated by Endogenous Opioid Activity on µ-Opioid
Receptors. J
Neuroscience 2005, 25(34):7754-7762. [Placebos' Effects Pinpointed
in Brain ScienceNOW and Eurekalert]
- Trust for Americn's Health Report: How
Obesity Policies are Failing in America 2005
- Listeria hijacks the clathrin-dependent endocytic machinery to invade
mammalian cells. Nature
Cell Biology 2005 online: 21 August 2005; doi:10.1038/ncb1292 [Eurekalert]
- Vaccine-induced tumor-specific immunity despite severe B-cell depletion
in mantle cell lymphoma, . Nature
Medicine Published online: 21 August 2005 | doi:10.1038/nm1290.[Eurekalert:
Immune system finding paves way for vaccine use in some leukemia, lymphoma
cancers]
| ::::::: August
25 ::::::: |
|
- JAMA Vol.
294 No. 8 August 24/31, 2005
- Randomised trial of telephone intervention in chronic heart failure:
DIAL trial. BMJ
2005;331:425 (20 August), doi:10.1136.
- Role of mobile phones in motor vehicle crashes resulting in hospital
attendance: a case-crossover study. BMJ
2005;331:428 (20 August), doi:10.1136.
- Early invasive strategy in elderly patients with non ST elevation acute
coronary syndrome: Comparison with younger patients on 30-day and long-term
outcome. Heart
Online First: doi:10.1136/hrt.2004.051607 [Eurekalert]
- Ovarian cancer: Can we make the clinical diagnosis earlier? Cancer
online: 22 Aug 2005 DOI: 10.1002/cncr.21310. [Eurekalert]
- Youth Football: Heat Stress and Injury Risk. Early
release: Medicine & Science in Sports & Exercise.
| ::::::: August
24 ::::::: |
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- New
England Journal of Medicine Volume 353 August 18, 2005 Number 7
- Dietary Calcium Intake Protects Women Consuming Oral Contraceptives From
Spine and Hip Bone Loss. J.
Clin. Endocrinol. Metab.Published online doi:10.1210/jc.2004-0924.
- Prevalences of positive skin test responses to 10 common allergens in
the US population: Results from the Third National Health and Nutrition
Examination Survey. J
Allergy Clin Immunol 2005;116:377-383. [Medscape]
- Large Meta-Analysis Establishes the ACE Insertion-Deletion Polymorphism
as a Marker of Alzheimer's Disease . Am
J Epidemiol 2005;162:305-317. [Medscape]
| ::::::: August
23 ::::::: |
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- Annals of Internal
Medicine 16 August 2005 Volume 143 Issue 4
- Early Release: Late Restenosis in Patients
Receiving a Polymer-Coated Sirolimus-Eluting Stent. Wessely,
and others.
- Warfarin plus Aspirin after Myocardial Infarction
or the Acute Coronary Syndrome: Meta-Analysis with Estimates of
Risk and Benefit. Rothberg,
and Others.[Medscape]
- Clinical Outcomes and Cost-Effectiveness of Strategies
for Managing People at High Risk for Diabetes. Eddy
and Others
- A Prognostic Index for Systemic AIDS-Related Non-Hodgkin
Lymphoma Treated in the Era of Highly Active Antiretroviral Therapy. Bower,
and others.
- Quality of Care Is Associated with Survival in
Vulnerable Older Patients. Higashi,
and others
- Evaluation and Management of the Patient with
Pulmonary Arterial Hypertension. Rubin
and Badesch
- Promoting Informed Choice: Transforming Health
Care To Dispense Knowledge for Decision Making. Woolf,
and others
- EDITORIALS: Trying To Predict the Future for People
with Diabetes: A Tough but Important Task. Engelgau
- Modeling Complex Medical Decision Problems with
the Archimedes Model. Brandeau
- Improving Patient Care Can Set Your Brain on Fire. Williams
- ON BEING A DOCTOR: Lessons from a Patient. Rifkin
- * Clinical Performance
Measures for Adults with Chronic Heart Failure and the ACC/AHA Key Data
Elements and Definitions for Measuring Clinical Measurements and Outcomes
of Patients with Chronic Heart Failure. Guidelines for Diagnosis and Treatment
of Heart Failure Update by. American College of Cardiology / American
Heart Association .Summary (pdf)
and Full
text. (pdf).
[Medscape andEurekalert review]
| ::::::: August
22 ::::::: |
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- Non-Narcotic Analgesic Dose and Risk of Incident Hypertension in US Women. Hypertension
published August 15, 2005. [Medscape and Eurekalert]
- Anemia and Change in Hemoglobin Over Time Related to Mortality and Morbidity
in Patients With Chronic Heart Failure. Results From Val-HeFT. Circulation
2005: published online 10.1161 [Eurekalert]
- Selective Cyclooxygenase-2 Inhibitors Development in Cardiovascular Medicine. Circulation
2005 112: 1073 - 1079.
- Should Aspirin Be Discontinued Before Coronary Artery Bypass Surgery? Circulation
2005 112: e85 - e90.
- JAMA
Vol. 294 No. 7, pp. 773-866, August 17, 2005
- Impact of Varicella Vaccination on Health Care
Utilization. JAMA.
2005;294:797-802.
- * Relationship
Between Time of Day, Day of Week, Timeliness of Reperfusion, and
In-Hospital Mortality for Patients With Acute ST-Segment Elevation
Myocardial Infarction. JAMA.
2005;294:803-812. [Medscape]
- * Acute
Renal Failure in Critically Ill Patients: A Multinational, Multicenter
Study. JAMA.
2005;294:813-818. [Medscape]
- Reviews: Sirolimus-Eluting Stents vs Paclitaxel-Eluting
Stents in Patients With Coronary Artery Disease: Meta-analysis
of Randomized Trials. JAMA.
2005;294:819-825.
- Quantifying the Federal Minimal Risk Standard:
Implications for Pediatric Research Without a Prospect of Direct
Benefit. JAMA.
2005;294:826-832.
- Medical Marijuana, American Federalism, and the
Supreme Court. JAMA.
2005;294:842-844.
- Editorials: Varicella Vaccine, Cost-effectiveness
Analyses, and Vaccination Policy. JAMA.
2005;294:845-846.
| ::::::: August
19 ::::::: |
Weekend
Reading - Basic Science and general interest articles
|
|
- FDA Approvals: [Medscape]
- Fortical (calcitonin-salmon [rDNA
origin] nasal spray) for treatment of osteoporosis in women more
than five years after menopause with low bone mass.
- Actonel With Calcium (35-mg risedronate
sodium | 1,250-mg calcium carbonate tablets) for treatment and
prevention of osteoporosis in postmenopausal women.
- VAQTA (inactivated hepatitis A
vaccine) allowing use in patients as young as 12 months. The vaccine
was previously approved for use in patients aged two years and
older.
- FDA
Safety Alert: Isotretinoin - Accutane
and generic isotretinoin. FDA Approves iPLEDGE Risk Management Program
for Accutane. [Medscape]
- FDA Approves New Glucose Monitoring System [Medscape]
- * Allosteric
Modulation of the RNA Polymerase Catalytic Reaction Is an Essential Component
of Transcription Control by Rifamycins. Cell,
Vol 122, 351-363, 12 August 2005. [Researchers find how some antibiotics
kill bacteria journal Eurekalert]
- Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis
disease. PNAS
published August 15, 2005 [Eurekalert:
Scientists discover gene that controls speed of tuberculosis development.]
- Radiotherapy After Radical Prostatectomy Cuts Biochemical Progression
Risk. Medscape review
of article in Lancet (limited access)
- Early research suggests a potential way to eradicate dormant HIV infection,
scientists claim in the Lancet.[BBC
News]
| ::::::: August
18 ::::::: |
|
- Archives
of Internal MedicineVol. 165 No. 15 Aug 8/22, 2005
- The impact of standardized stroke orders on adherence to best practices. Neurology
2005 65: 360-365.
- The Effects of Prolonged Ethanol Exposure on the Mechanical Properties
of Polyurethane and Silicone Catheters Used for Intravascular Access. Maki
and others. Inf Control
Hosp Epidemiology 2005; 26 [Eurekalert]
- * Snoring Imaging:
Could Bernoulli Explain It All? Chest
2005 128: 896-901.
| ::::::: August
17 ::::::: |
|
- New
England Journal of Medicine Volume 353 Number 6 August
11, 2005
| ::::::: August
12 ::::::: |
Weekend
Reading - Basic Science and general interest articles
|
|
- * Sleep-disordered
breathing after targeted ablation of preBötzinger complex neurons.
Published online: Nature
Neuroscience 07 August 2005 doi:10.1038/nn1517. [Eurekalert and Science
Daily]
- FDA Approvals: [Medscape]
- Naglazyme (galsulfase)
to improve walking and stair-climbing capacity in patients with
mucopolysaccharidosis VI.
- Trizivir (combination abacavir
sulfate, lamivudine, and zidovudine) allowing use alone or in combination
with other antiretroviral agents for the treatment of HIV-1.
- Levaquin (levofloxacin) {new
indication} five-day dosing regimen for the treatment of acute
bacterial sinusitis (ABS) due to Streptococcus pneumoniae, Haemophilus
influenzae, and Moraxella catarrhalis in adults.
- FDA Safety Labeling Changes: [Medscape]
- Arixtra (fondaparinux)
contraindications and warnings: prophylactic therapy is contraindicated
in patients weighing less than 50 kg , in patients with severe
renal impairment (creatinine clearance [CrCl], < 30 mL/minute),
caution with moderate renal impairment (CrCl, 30 - 50 mL/minute).
risk of thrombocytopenia.
- Alora (extended-release estradiol
transdermal) contraindications and warnings in individuals with
liver dysfunction/disease or those with a hypersensitivity to its
ingredients.
- Location analysis of estrogen receptor target promoters reveals that
FOXA1 defines a domain of the estrogen response. PNAS
published August 8, 2005, 10.1073/pnas.0505575102. [Scientists discover
genetic pathway responsible for breast cancer cell growth. Eurekalert]
- Obese people are less likely to receive health services [Science
Daily] Am J Public Health sept
[Eurekalert]
- Alterations in the 2 isoform of Na,K-ATPase associated with familial
hemiplegic migraine type 2. PNAS
2005 102: 11106-11111 [Science
Daily]
- Paternal Discrepancy Not Uncommon. [Medscape report
from J Epidemiol
Community Health, 2005;59:749-754..]
- FDA
MedWatch: Public Health Notification of serious complications associated
with the use of metallic tracheal stents in patients with benign airway
disorders
| ::::::: August
11 ::::::: |
|
- Masked Hypertension May Mandate Aggressive Screening and Treatment .
J Am Coll Cardiol. 2005;46:508-515 [Medscape]
- JAMA
Vol. 294 No. 6, August 10, 2005
| ::::::: August
10 ::::::: |
|
- Differential expression of cannabinoid receptors in the human colon:
Cannabinoids promote epithelial wound healing. Gastroenterology
2005; 129:437-453. [Cannabis may soothe inflamed bowels. New
Scientist
- Probability of Pancreatic Cancer Following Diabetes: A Population-Based
Study. Gastroenterology
2005; 129: 504-511. [Eurekalert and Eurekalert]
- Angiotensin-Converting Enzyme Inhibitors and Calcium Channel Blockers
for Coronary Heart Disease and Stroke Prevention. Hypertension
2005;46:386-392. [Medscape]
- Subcutaneous Use of a Fast-Acting Insulin Analog: An alternative treatment
for pediatric patients with diabetic ketoacidosis. Diabetes
Care 2005 28: 1856-1861. [Medscape]
- Autoantibodies to Autonomic Nerves Associated With Cardiac and Peripheral
Autonomic Neuropathy. Diabetes
Care 2005 28: 1959-1964. [Medscaape]
- Rheumatoid arthritis is an independent risk factor for multi-vessel coronary
artery disease: a case control study. Arthritis
Research & Therapy 2005, 7:R984-R991 [Medscape]
- Infliximab improves signs and symptoms of psoriatic arthritis: results
of the IMPACT 2 trial. Ann
Rheum Dis 2005 64: 1150 -1157. [Medscape]
- CDC Morbidity and Mortality Weekly
Report.[Medscape report]
- AHA Scientific Statement: Practical Implementation of the Guidelines
for Unstable Angina/Non–ST-Segment Elevation Myocardial Infarction
in the Emergency Department. Circulation.
2005;111:2699-2710 and Annals
Emerg Med 2005; 46: 185-197. [Eurekalert]
- Women patients' preference for women physicians is a barrier to colon
cancer screening. Gastroint
Endosc 2005; 62: 219-223. [Eurekalert]
- Dopamine-Independent Locomotor Actions of Amphetamines in a Novel Acute
Mouse Model of Parkinson Disease: PLoS
Biology (vol 3, p e271) [NewScientist]
- Do drug samples influence resident prescribing behavior? A randomized
trial. Am
J Med 2005; 118:881-884. [Eurekalert]
- A Randomized, Double-Blind, Placebo-Controlled Trial of Pramipexole,
a Dopamine Agonist, in Patients With Fibromyaglia Receiving Concomitant
Medications. Arthritis & Rheumatism
2005; 52:2495-2505. [Eurekalert]
- BMJ 6
August 2005 (Vol 331, No 7512)
- * How
strong is the evidence for the use of perioperative blockers in
non-cardiac surgery? Systematic review and meta-analysis of randomised
controlled trials. BMJ
2005:313-321,.
- Effects of locality based community hospital care
on independence in older people needing rehabilitation: randomised
controlled trial. BMJ
2005:317-322.
- Intermediate care: policy before evidence. BMJ
2005:320.
- Cholinesterase inhibitors for patients with Alzheimer's
disease: systematic review of randomised clinical trials. BMJ
2005:321-327,
- * Effect
of multivitamin and multimineral supplements on morbidity from
infections in older people (MAVIS trial): pragmatic, randomised,
double blind, placebo controlled trial. BMJ
2005:324-329.
- Antibiotic prescribing in general practice and
hospital admissions for peritonsillar abscess, mastoiditis, and
rheumatic fever in children: time trend analysis. BMJ
2005:328-329
- 10-minute consultation: Anaphylaxis. BMJ
2005:330
- New
England Journal of Medicine Volume 353 August 4, 2005 Number 5
| ::::::: August
5 ::::::: |
Weekend
Reading - Basic Science and general interest articles
|
|
- FDA Approvals: [Medscape]
- Diovan, (valsartan)
approval to reduce the risk of cardiovascular mortality in clinically
stable patients with left ventricular dysfunction/failure following
myocardial infarction.
- Celebrex, (celecoxib) for the relief
of signs and symptoms of ankylosing spondylitis.
- Adderall XR (mixed salts of a single-entity
amphetamine product) allowing its use as once-daily treatment for attention-deficit/hyperactive
disorder (ADHD) in adolescents aged 13 to 17 years.
- First-Time Generic Approvals: Nydrazid, Aclovate, Allegra. [Medscape]
- International Approvals: Orphan Drug Approvals: Pegylated Arginine Deiminase,
Beta-1,3/1,6-Glucan, Stem Cell Product [Medscape]
- Curbing the Influence of the Drug Industry: A British View. PLoS
Med 2(9): e241
- Which Treatment for Postherpetic Neuralgia? PLoS
Med 2(7): e238 [Science
Daily]
- Using Search Engines to Find Online Medical Information. PLoS
Med 2(9): e228
- ROS generated by pollen NADPH oxidase provide a signal that augments
antigen-induced allergic airway inflammation. J.
Clin. Invest. 2005 115: 2169-2179.
- Most patients can't recall own diagnosis [Science
Daily report from Lancet(not available online)]
- * Striking deposition
of toxic eosinophil major basic protein in mucus: Implications for chronic
rhinosinusitis. J
Allergy Clin Imm 2005; 116: 362-369 [Eurekalert and Medscape:
Cause of Chronic Sinus Infection Lies in Nasal Mucus, Not Tissue]
- Heparinase I Compared with Protamine for Heparin Reversal after Coronary
Artery Bypass Graft. Anesthesiology
2005; 103: 229. [Eurekalert:
New anti-blood-thinning drug not as safe as protamine]
- * Fatal Interaction
between Clarithromycin and Colchicine in Patients with Renal Insufficiency:
A Retrospective Study . Clin
Infect Dis 2005;41:291-300.[Medscape]
- Increased Risk of Common Infections in Patients with Type 1 and Type
2 Diabetes Mellitus. Clin
Infect Dis 2005;41:281-288.
- JAMA Vol.
294 No. 5, pp. 523-646, August 3, 2005
- Rates of Adult Schizophrenia Following Prenatal
Exposure to the Chinese Famine of 1959-1961. JAMA
2005;294:557-562.
- Cognitive Therapy for the Prevention of Suicide
Attempts: A Randomized Controlled Trial. JAMA
2005;294:563-570.
- Mental Health of Cambodian Refugees 2 Decades
After Resettlement in the United States. JAMA
2005;294:571-579.
- Psychiatric and Cognitive Effects of War in Former
Yugoslavia: Association of Lack of Redress for Trauma and Posttraumatic
Stress Reactions. JAMA
2005;294:580-590.
- Assessment of Severe Malnutrition Among Hospitalized
Children in Rural Kenya: Comparison of Weight for Height and Mid
Upper Arm Circumference. JAMA
2005;294:591-597.
- Criminal Records of Homicide Offenders. JAMA
2005;294:598-601.
- Reviews: Predisplacement and Postdisplacement
Factors Associated With Mental Health of Refugees and Internally
Displaced Persons: A Meta-analysis. JAMA
2005;294:602-612.
- Women in Rwanda: Another World Is Possible. JAMA
2005;294:613-615.
- Binge Drinking and Violence. JAMA
2005;294:616-618.
- Family Violence Research: Lessons Learned and
Where From Here? JAMA
2005; 294:618-620.
- Editorials: Accumulating Evidence for Prenatal
Nutritional Origins of Mental Disorders. JAMA
2005;294:621-623.
- Mental Illness and Violent Death: Major Issues
for Public Health. JAMA
2005;294:623-624.
- Sex Differences in the Clinical Manifestations of Alzheimer Disease Pathology. Arch
Gen Psychiatry. 2005;62:685-691.
- VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative
Colitis. Am
J Gastroenterology 2005; 100: 1539. [Eurekalert]
- Mortality in US Army Gulf War Veterans Exposed to 1991 Khamisiyah Chemical
Munitions Destruction. Am
J Public Health 2005 95: 1382-1388. [Eurekalert]
- * Systematic
comparison of four sources of drug information regarding adjustment of
dose for renal function. BMJ
2005;331:263 and BMJ
2005;331:29
- * Systematic
review and meta-analysis of strategies for the diagnosis of suspected pulmonary
embolism. BMJ
2005:331:259.
- Annals of Internal
Medicine 2 August 2005 Volume 143 Issue 3
- The Costs of a National Health Information Network. Kaushal,
and Others.
- Comparing the Risk for Death with Peritoneal Dialysis and Hemodialysis
in a National Cohort of Patients with Chronic Kidney Disease. Jaar,
and Others.
- A Randomized Trial of Ways To Describe Test Accuracy: The Effect
on Physicians' Post-Test Probability Estimates. Puhan,
and Others.
- Update in General Internal Medicine. Sheffield
and Larson
- Narrative Review: Screening for Colorectal Cancer in Patients with
a First-Degree Relative with Colonic Neoplasia. Eisen
and Weinberg
- Meta-Analysis: Obesity and the Risk for Gastroesophageal Reflux
Disease and Its Complications. Hampel,
and Others.
- Perspectives: Electronic Health Records: Just around the Corner?
Or over the Cliff? Baron,
and Others
- Editorials: Electronic Health Records and the National Health Information
Network: Affordable, Adoptable, and Ready for Prime Time? Basch
- Mortality and Treatment Modality of End-Stage Renal Disease. Schulman
- An Editorial Update: Should Benefits of Radical Prostatectomy
Affect the Decision To Screen for Early Prostate Cancer? Sox
and Mulrow
- On Being a Doctor: A Little Confidence. Le
- Leukotriene Modifier Therapy for Mild Sleep-disordered Breathing in Children. Am
J Respir Crit Care Med 2005; 172: 364-370. [Eurekalert]
- Occupational Asthma. Am.
J. Respir. Crit. Care Med. 2005; 172: 280-305. [Eurekalert]
- Severe Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease. Am
J Respir Crit Care Med. 2005; 172: 189-194. [Medscape]
- Cortisol, Testosterone, and Coronary Heart Disease: Prospective Evidence
From the Caerphilly Study. Circulation
2005 112: 332 - 340.
- Statin Therapy May Be Associated With Lower Mortality in Patients With
Diastolic Heart Failure: A Preliminary Report Circulation
2005 112: 357 - 363. [Eurekalert]
- JAMA. Vol.
294 No. 4 July 27, 2005
- New
England Journal of Medicine Volume 353 July 28, 2005 Number 4